Gene Symbol | SULT4A1 |
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Entrez Gene | 25830 |
Alt Symbol | BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1 |
Species | Human |
Gene Type | protein-coding |
Description | sulfotransferase family 4A, member 1 |
Other Description | ST4A1|brain sulfotransferase-like protein|hBR-STL|nervous system cytosolic sulfotransferase|nervous system sulfotransferase|sulfotransferase 4A1|sulfotransferase-related protein |
Swissprots | Q9BR01 O43728 B2R7N3 |
Accessions | EAW73317 EAW73318 EAW73319 EAW73320 Q9BR01 AF115311 AAF21970 AF176342 AAK64595 AF188698 AAF61197 AF251263 AAF98152 AK091700 AK294622 BAH11827 AK295399 BAH12056 AK313048 BAG35880 AL590119 CAC34872 BC022459 AAH22459 BC028171 AAH28171 BC030665 AAH30665 CR456588 CAG30474 CU013188 CAK54619 CU013476 CAK54918 DQ892373 ABM83299 DQ895583 ABM86509 XM_011530120 XP_011528422 XM_011530121 XP_011528423 XR_937838 XR_937839 NM_014351 NP_055166 NM_176874 |
Function | Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS. {ECO:0000269|PubMed:17425406}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe, slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030). {ECO:0000269|PubMed:10698717, ECO:0000269|PubMed:12039030}. |
SULT4A1 CRISPR/Cas9 KO Plasmid (h) - sc-406385 from Santa Cruz Biotechnology
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SULT4A1 HDR Plasmid (h) - sc-406385-HDR from Santa Cruz Biotechnology
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SULT4A1 Double Nickase Plasmid (h) - sc-406385-NIC from Santa Cruz Biotechnology
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SULT4A1 Double Nickase Plasmid (h2) - sc-406385-NIC-2 from Santa Cruz Biotechnology
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SULT4A1 CRISPR Activation Plasmid (h) - sc-406385-ACT from Santa Cruz Biotechnology
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SULT4A1 CRISPR Activation Plasmid (h2) - sc-406385-ACT-2 from Santa Cruz Biotechnology
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SULT4A1 Lentiviral Activation Particles (h) - sc-406385-LAC from Santa Cruz Biotechnology
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SULT4A1 Lentiviral Activation Particles (h2) - sc-406385-LAC-2 from Santa Cruz Biotechnology
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SULT4A1 siRNA (h) - sc-76609 from Santa Cruz Biotechnology
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SULT4A1 shRNA Plasmid (h) - sc-76609-SH from Santa Cruz Biotechnology
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SULT4A1 shRNA (h) Lentiviral Particles - sc-76609-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU066141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20827 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20827 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09416 from Sigma-Aldrich
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SULT4A1 siRNA (Human) - CRH8528 from Cohesion Biosciences
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SULT4A1 - MBS8234242 from MyBioSource
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shRNA set against Human SULT4A1 (NM_014351.3) - SHH420844 from Creative biogene
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shRNA set against Human SULT4A1(NM_014351.3) - SHL047736 from Creative biogene
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SULT4A1 shRNA Plasmid (Human) - CHH8528 from Cohesion Biosciences
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SULT4A1 miRNA 3'UTR clone - MiUTR1H-10059 from Creative biogene
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