| Gene Symbol |
SULT4A1
|
| Entrez Gene |
25830
|
| Alt Symbol |
BR-STL-1, BRSTL1, DJ388M5.3, NST, SULTX3, hBR-STL-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sulfotransferase family 4A, member 1
|
| Other Description |
ST4A1|brain sulfotransferase-like protein|hBR-STL|nervous system cytosolic sulfotransferase|nervous system sulfotransferase|sulfotransferase 4A1|sulfotransferase-related protein
|
| Swissprots |
Q9BR01 O43728 B2R7N3
|
| Accessions |
EAW73317 EAW73318 EAW73319 EAW73320 Q9BR01 AF115311 AAF21970 AF176342 AAK64595 AF188698 AAF61197 AF251263 AAF98152 AK091700 AK294622 BAH11827 AK295399 BAH12056 AK313048 BAG35880 AL590119 CAC34872 BC022459 AAH22459 BC028171 AAH28171 BC030665 AAH30665 CR456588 CAG30474 CU013188 CAK54619 CU013476 CAK54918 DQ892373 ABM83299 DQ895583 ABM86509 XM_011530120 XP_011528422 XM_011530121 XP_011528423 XR_937838 XR_937839 NM_014351 NP_055166 NM_176874
|
| Function |
Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS. {ECO:0000269|PubMed:17425406}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in the cerebral cortex and frontal lobe, slightly less in the cerebellum, occipital and temporal lobes, relatively low in the medulla and putamen, and lowest in the spinal cord. No expression detected in the pancreas (PubMed:10698717). Highly expressed in fetal brain and occipital lobe, slightly less in the whole brain, frontal lobe, hippocampus, and lung, very low expression in cerebellum, medulla oblongata, temporal lobe, testis, kidney and appendix (PubMed:12039030). {ECO:0000269|PubMed:10698717, ECO:0000269|PubMed:12039030}.
|