UBE2D1

Gene Symbol	UBE2D1
Entrez Gene	7321
Alt Symbol	E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
Species	Human
Gene Type	protein-coding
Description	ubiquitin-conjugating enzyme E2D 1
Other Description	UBC4/5 homolog|stimulator of Fe transport|ubiquitin carrier protein D1|ubiquitin-conjugating enzyme E2 D1|ubiquitin-conjugating enzyme E2(17)KB 1|ubiquitin-conjugating enzyme E2-17 kDa 1|ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)|ubiquitin-protein ligase D1
Swissprots	A8K786 P51668 A6NLF6
Accessions	CAC82097 EAW54167 EAW54168 EAW54169 EAW54170 P51668 AF020761 AF257220 AAM81086 AI566662 AJ272367 CAC82177 AK291901 BAF84590 BC005980 AAH05980 BC015997 AAH15997 BI598342 BM468116 BM970335 BT007041 AAP35690 DA618122 DA677507 DQ893111 ABM84037 DQ896385 ABM87384 X78140 CAA55019 NM_001204880 NP_001191809 NM_003338 NP_003329
Function	Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4. {ECO:0000269|PubMed:18042044, ECO:0000269|PubMed:18359941, ECO:0000269|PubMed:19103148, ECO:0000269|PubMed:19854139, ECO:0000269|PubMed:20061386}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:18845142}.
Tissue Specificity	Ubiquitous. Up-regulated in livers of iron- overloaded patients with hereditary hemochromatosis. {ECO:0000269|PubMed:12480712, ECO:0000269|PubMed:9362508}.
Top Pathways	Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human UBE2D1 gene - orb91944 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-UBE2D1-cDNA-Clone - DC01835 from Abgent, a WuXi AppTec company Prices $198.45 Sizes 10 µg Species Human Accession NM_003338

UBE2D1 - MBS1274521 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC005980

Human UBE2D1 ORF Clone(NM_003338.4) - CDCL180268 from Creative Biomart Species Human Accession NM_003338.4

human UBE2D1 ORF clone - CDCH097348 from Creative Biomart Species Human Accession NM_001204880

human UBE2D1 ORF clone - CDCH097349 from Creative Biomart Species Human Accession NM_001204880

human UBE2D1 ORF clone - CDCH097350 from Creative Biomart Species Human Accession NM_001204880

human UBE2D1 ORF clone - CDCH097351 from Creative Biomart Species Human Accession NM_001204880

Human UBE2D1 Gene cDNA clone plasmid - HG11432-M from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid - HG11432-UT from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11432-ACG from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11432-NH from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11432-CH from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11432-ANG from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11432-NF from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11432-NM from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11432-CF from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11432-CM from Sino Biological Species Human

Human UBE2D1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11432-M-N from Sino Biological Species Human Accession NM_003338.3

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11432-ACR from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11432-ANR from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11432-NY from Sino Biological Species Human

Human UBE2D1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11432-CY from Sino Biological Species Human

human UBE2D1 ORF clone (NM_001204880.1) - CDCH097350 from Creative biogene Species Human

Human UBE2D1 ORF Clone (BC005980) - CDCS409641 from Creative biogene Species Human Accession P51668

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