Prmt1

Gene Symbol	Prmt1
Entrez Gene	15469
Alt Symbol	6720434D09Rik, AW214366, Hrmt1l2, Mrmt1
Species	Mouse
Gene Type	protein-coding
Description	protein arginine N-methyltransferase 1
Other Description	arginine N-methyltransferase 1|heterogeneous nuclear ribonucleoproteins methyltransferase-like 2|histone-arginine N-methyltransferase PRMT1
Swissprots	Q9JIF0 Q99LS4
Accessions	AAF37294 EDL22776 EDL22777 EDL22778 EDL22779 Q9JIF0 AF232716 AAF37292 AF232717 AAF37293 AI846916 AK020120 BAB32002 AK088790 BAC40573 AK146927 BAE27538 AK146975 AK152342 AK164421 BAE37781 AK179815 AK181903 AK182201 AK182363 AK198313 AK216645 AK217171 BC002249 AAH02249 BC051547 AAH51547 BC051953 AAH51953 BC062964 AAH62964 BU524421 BY760714 W49313 XM_006540640 XP_006540703 XM_011250807 XP_011249109 NM_001252476 NP_001239405 NM_001252477 NP_001239406 NM_019830 NP_062804 NR_045521
Function	Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. {ECO:0000269|PubMed:15327772, ECO:0000269|PubMed:19858291}.
Subcellular Location	Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytosol. Note=Mostly found in the cytoplasm. Colocalizes with CHTOP within the nucleus. Low levels detected also in the chromatin fraction.
Top Pathways	Glucagon signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PRMT1 Protein - NBC1-18445 from Novus Biologicals Category Protein Prices $249.00 Sizes 100 µg Species Mouse

PRMT1 Recombinant Protein - P4330 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Mouse

PRMT1 Protein - NBP1-99160 from Novus Biologicals Category Protein Species Mouse

Recombinant Mouse PRMT1 Protein - NBP1-99560 from Novus Biologicals Category Protein Prices $260.00 Sizes 50 µg Source E. coli

PRMT1 Protein (OPPA01694) - OPPA01694 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Mouse PRMT1 protein (isoform 2) (MBP tag) - 80R-1041 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli Species Mouse

PRMT1 protein - 30R-2391 from Fitzgerald Category Protein Prices $100.00 Sizes 10 µg Source E.coli Species Mouse

PRMT1 (Isoform 2) (1-353, His-MBP-tag) - AR09075PU-L from Acris Antibodies Category Protein Prices $585.00 Sizes 500 µg Source E. coli Species Mouse

PRMT1 (Isoform 2) (1-353, His-MBP-tag) - AR09075PU-N from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Mouse

PRMT1 - P4330 from Acris Antibodies Category Protein Prices $430.00 Sizes 100 µg Species Mouse

Protein Arginine Methyltransferase 1, Mouse Recombinant - 228-11314-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Mouse

Recombinant Mouse PRMT1 - 228-11314-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Mouse

Recombinant Mouse PRMT1 - 228-11314-3 from RayBiotech Category Protein Prices $1,950.00 Sizes 3 µg Source Escherichia Coli. Species Mouse

Mouse PRMT1 isoform2, 1-353 aa, mouse, His-MBP tagged, Recombinant, E.coli - 01-2291 from ARP American Research Products Category Protein Prices $139.00, $299.00, $639.00 Sizes 20 µg, 100 µg, 500 µg Source E.coli Species Mouse

Mouse PRMT1 isoform2, 1-353 aa, Recombinant Protein - GWB-P0077L from Genway Biotech Category Protein Prices $210.00, $630.00 Sizes 100 μg, 500 μg Source E.coli Species Mouse

Recombinant Mouse Protein Arginine Methyltransferase 1 - GWB-79402A from Genway Biotech Category Protein Prices $75.00, $165.00, $1,195.00 Sizes 10 μg, 50 μg, 1000 μg Species Mouse

Recombinant Mouse Protein Arginine N-methyltransferase 1, His-MBP-tagged - Prmt1-1762M from Creative Biomart Category Protein Source Mouse

Mouse PRMT1 isoform2 1-353 aa - PRM-233 from Reagent Proteins Category Protein Prices $406.00, $700.00 Sizes 100.00 µg, 500 µg Source E.coli Species Mouse

PRMT1 - PAT-80186-0 from Nordic BioSite Category Protein Species Mouse

PRMT1 - PAT-80186-1 from Nordic BioSite Category Protein Species Mouse

Recombinant Mouse Protein arginine N-methyltransferase 1(Prmt1) - CSB-YP878062MO CSB-EP878062MO CSB-BP878062MO CSB-MP878062MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Mouse PRMT1 isoform2, 1-353aa, mouse, His-MBP tag, E.coli (Bioactivity Validated) - PRM0801 from ATGen Category Protein Prices $55.00, $170.00, $505.00 Sizes 20 µg, 100 µg, 500 µg Species Mouse

PRMT1, mouse recombinant (Active) - 4868-10 from Biovision Category Protein Prices $80.00 Sizes 10 μg Source E. coli Species Mouse

PRMT1, mouse recombinant (Active) - 4868 -50 from Biovision Category Protein Prices $260.00 Sizes 50 μg Source E. coli Species Mouse

PRMT1, mouse recombinant (Active) - 4868-1000 from Biovision Category Protein Prices $2,900.00 Sizes 1 mg Source E. coli Species Mouse

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