Gene Symbol | DDAH2 |
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Entrez Gene | 23564 |
Alt Symbol | DDAH, DDAHII, G6a, HEL-S-277, NG30 |
Species | Human |
Gene Type | protein-coding |
Description | dimethylarginine dimethylaminohydrolase 2 |
Other Description | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2|S-phase protein|dimethylargininase-2|dimethylarginine dimethylaminohydrolase II|epididymis secretory protein Li 277 |
Swissprots | A2BEZ7 O95865 |
Accessions | AAD18074 BAB63377 CAB46079 EAX03500 EAX03501 EAX03502 O95865 AA297871 AF070667 AAD20973 AF087894 AAP97193 AK026191 AK098671 AK310024 BC001435 AAH01435 BF338733 CB242623 EB387244 FJ224290 ACI45982 XM_011514448 XP_011512750 XM_011547196 XP_011545498 XM_011547610 XP_011545912 XM_011547847 XP_011546149 XM_011548016 XP_011546318 XM_011548205 XP_011546507 XM_011548389 XP_011546691 NM_001303007 NP_001289936 NM_001303008 NP_001289937 NM_013974 NP_039268 |
Function | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. {ECO:0000269|PubMed:10493931}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21898353}. Mitochondrion {ECO:0000269|PubMed:21898353}. Note=Translocates from cytosol to mitochondrion upon IL-1beta stimulation in chondrocytes. |
Tissue Specificity | Detected in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas, and at very low levels in brain. {ECO:0000269|PubMed:10493931}. |
Human DDAH2 peptide - ab22866 from Abcam
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DDAH1 Antibody Blocking Peptide - LS-E25284 from LifeSpan Bioscience
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DDAH1 Antibody Blocking Peptide - LS-E7187 from LifeSpan Bioscience
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DDAH1 Antibody Blocking Peptide - LS-E19779 from LifeSpan Bioscience
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DDAH1 Antibody Blocking Peptide - LS-E19780 from LifeSpan Bioscience
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DDAH2 Antibody Blocking Peptide - LS-E25283 from LifeSpan Bioscience
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DDAH2 Antibody Blocking Peptide - LS-E21455 from LifeSpan Bioscience
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DDAH2 Blocking Peptide - NBP1-58859PEP from Novus Biologicals
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DDAH2 Recombinant Protein - H00023564-P01 from Novus Biologicals
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DDAH2-Antibody-Center-Blocking-peptide - BP10387c from Abgent, a WuXi AppTec company
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DDAH2-Antibody-Center-Blocking-peptide - BP12237c from Abgent, a WuXi AppTec company
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DDAH2 blocking peptide - GTX89963-PEP from GeneTex
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DDAH2 Blocking Peptide - 33R-6631 from Fitzgerald
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Human DDAH2 Protein - abx066342 from Abbexa
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DDAH2 Peptide - AC21-0111-P from Abcore
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Dimethylarginine Dimethylaminohydrolase 2 (DDAH2), Human - 20-8872 from ARP American Research Products
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DDAH2 Peptide - 45-469P from ProSci
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DDAH2 fusion protein - Ag7127 from Proteintech Group
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DDAH2 fusion protein - Ag6831 from Proteintech Group
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DDAH1 Human - ENPS-021 from NeoScientific
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Recombinant Human DDAH2, His-tagged - DDAH2-26260TH from Creative Biomart
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Recombinant Human DDAH2, His-tagged - DDAH2-11876H from Creative Biomart
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DDAH1 - JNV-059 from Reagent Proteins
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Recombinant Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) - RPD981Hu01 from Uscn Life Science Inc.
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Recombinant Dimethylarginine Dimethylaminohydrolase 2 (DDAH2) - RPD981Hu01 from Cloud-clone
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