Gene Symbol | CAPN2 |
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Entrez Gene | 281662 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | calpain 2, (m/II) large subunit |
Other Description | CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain M-type|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar-calpain |
Swissprots | Q27971 A4IFD3 |
Accessions | DAA21366 Q27971 BC134526 AAI34527 U07850 AAA18455 NM_001103086 NP_001096556 |
Function | Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon Ca(2+) binding. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Apoptosis, Focal adhesion, Alzheimer's disease, Protein processing in endoplasmic reticulum |
CAPN2 Protein (OPPA01245) - OPPA01245 from Aviva Systems Biology
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Native Bovine CAPN2 - 228-10170-1 from RayBiotech
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Native Bovine CAPN2 - 228-10170-2 from RayBiotech
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Native Bovine CAPN2 - 228-10170-3 from RayBiotech
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Native Bovine CAPN2 - CAPN2-350B from Creative Biomart
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Calpain-2 Catalytic Subunit, bovine - NKX-770 from Reagent Proteins
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Recombinant Bovine Calpain-2 catalytic subunit(CAPN2) ,partial - CSB-YP631683BO CSB-EP631683BO CSB-BP631683BO CSB-MP631683BO from Cusabio
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Calpain-2 catalytic subunit (CAPN2), partial, Recombinant Protein - MBS1424395 from MyBioSource
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Bovine Calpain-2 Catalytic Subunit - Pr20269 from ProMab
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Cow Calpain-2 Catalytic Subunit - abx263527 from Abbexa
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Bovine Calpain-2 Catalytic Subunit ( CAPN2 ) - PT_40082 from Novatein Biosciences
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