| Gene Symbol | CAPN2 |
|---|---|
| Entrez Gene | 281662 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | calpain 2, (m/II) large subunit |
| Other Description | CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain M-type|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar-calpain |
| Swissprots | Q27971 A4IFD3 |
| Accessions | DAA21366 Q27971 BC134526 AAI34527 U07850 AAA18455 NM_001103086 NP_001096556 |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Translocates to the plasma membrane upon Ca(2+) binding. {ECO:0000250}. |
| Tissue Specificity | Ubiquitous. |
| Top Pathways | Apoptosis, Focal adhesion, Alzheimer's disease, Protein processing in endoplasmic reticulum |
Calpain-2 catalytic subunit, CAPN2, Bovine, ELISA Kit - E2249b from ARP American Research Products
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calpain 2, (m/II) large subunit, ELISA Kit - MBS9332759 from MyBioSource
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Bovine CAPN2 ELISA Kit - E077275 from Biobool
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Calpain-2 catalytic subunit, ELISA Kit - MBS2880279 from MyBioSource
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