CAMKK1
| Gene Symbol | CAMKK1 |
|---|---|
| Entrez Gene | 84254 |
| Alt Symbol | CAMKKA |
| Species | Human |
| Gene Type | protein-coding |
| Description | calcium/calmodulin-dependent protein kinase kinase 1, alpha |
| Other Description | CAMKK alpha protein|caM-KK 1|caM-KK alpha|caM-kinase IV kinase|caM-kinase kinase 1|caM-kinase kinase alpha|caMKK 1|calcium/calmodulin-dependent protein kinase kinase 1|calcium/calmodulin-dependent protein kinase kinase alpha |
| Swissprots | Q9BQH3 Q8N5S9 |
| Accessions | EAW90474 EAW90475 EAW90476 Q8N5S9 AF370377 AAQ15213 AF425232 AAN37386 AF425301 AAN37387 AK128601 AL136576 CAB66511 BC011401 BC031647 AAH31647 BC043487 AAH43487 DQ892421 ABM83347 DQ895635 ABM86561 XM_005256817 XP_005256874 XM_006721588 XP_006721651 XM_011524030 XP_011522332 XM_011524031 XP_011522333 XM_011524032 XP_011522334 XM_011524033 XP_011522335 XM_011524034 XP_011522336 XM_011524035 XP_011522337 XR_934115 NM_032294 NP_115670 NM_172206 NP_757343 NM_172207 NP_757344 |
| Function | Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death. {ECO:0000269|PubMed:12935886}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Top Pathways | Adipocytokine signaling pathway, Alcoholism, Oxytocin signaling pathway, AMPK signaling pathway |
CaMKKα CRISPR/Cas9 KO Plasmid (h) - sc-402518 from Santa Cruz Biotechnology
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CaMKKα HDR Plasmid (h) - sc-402518-HDR from Santa Cruz Biotechnology
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CaMKKα Double Nickase Plasmid (h) - sc-402518-NIC from Santa Cruz Biotechnology
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CaMKKα Double Nickase Plasmid (h2) - sc-402518-NIC-2 from Santa Cruz Biotechnology
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CaMKKα CRISPR Activation Plasmid (h) - sc-402518-ACT from Santa Cruz Biotechnology
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CaMKKα CRISPR Activation Plasmid (h2) - sc-402518-ACT-2 from Santa Cruz Biotechnology
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CaMKKα Lentiviral Activation Particles (h) - sc-402518-LAC from Santa Cruz Biotechnology
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CaMKKα Lentiviral Activation Particles (h2) - sc-402518-LAC-2 from Santa Cruz Biotechnology
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CaMKKα siRNA (h) - sc-29904 from Santa Cruz Biotechnology
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CaMKKα shRNA Plasmid (h) - sc-29904-SH from Santa Cruz Biotechnology
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CaMKKα shRNA (h) Lentiviral Particles - sc-29904-V from Santa Cruz Biotechnology
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CaMKKα siRNA (h2) - sc-44293 from Santa Cruz Biotechnology
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CaMKKα shRNA Plasmid (h2) - sc-44293-SH from Santa Cruz Biotechnology
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CaMKKα shRNA (h2) Lentiviral Particles - sc-44293-V from Santa Cruz Biotechnology
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CaMKK alpha RNAi - H00084254-R01V from Novus Biologicals
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CaMKK alpha RNAi - H00084254-R05 from Novus Biologicals
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CaMKK alpha RNAi - H00084254-R06 from Novus Biologicals
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CaMKK alpha RNAi - H00084254-R04 from Novus Biologicals
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MISSION® esiRNA - EHU062291 from Sigma-Aldrich
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MISSION® siRNA - SIHK0264 from Sigma-Aldrich
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MISSION® siRNA - SIHK0265 from Sigma-Aldrich
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MISSION® siRNA - SIHK0266 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5322 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5322 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10689 from Sigma-Aldrich
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