Gene Symbol | CAMKK1 |
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Entrez Gene | 84254 |
Alt Symbol | CAMKKA |
Species | Human |
Gene Type | protein-coding |
Description | calcium/calmodulin-dependent protein kinase kinase 1, alpha |
Other Description | CAMKK alpha protein|caM-KK 1|caM-KK alpha|caM-kinase IV kinase|caM-kinase kinase 1|caM-kinase kinase alpha|caMKK 1|calcium/calmodulin-dependent protein kinase kinase 1|calcium/calmodulin-dependent protein kinase kinase alpha |
Swissprots | Q9BQH3 Q8N5S9 |
Accessions | EAW90474 EAW90475 EAW90476 Q8N5S9 AF370377 AAQ15213 AF425232 AAN37386 AF425301 AAN37387 AK128601 AL136576 CAB66511 BC011401 BC031647 AAH31647 BC043487 AAH43487 DQ892421 ABM83347 DQ895635 ABM86561 XM_005256817 XP_005256874 XM_006721588 XP_006721651 XM_011524030 XP_011522332 XM_011524031 XP_011522333 XM_011524032 XP_011522334 XM_011524033 XP_011522335 XM_011524034 XP_011522336 XM_011524035 XP_011522337 XR_934115 NM_032294 NP_115670 NM_172206 NP_757343 NM_172207 NP_757344 |
Function | Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death. {ECO:0000269|PubMed:12935886}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Top Pathways | Adipocytokine signaling pathway, Alcoholism, Oxytocin signaling pathway, AMPK signaling pathway |
Active human CaMKK full length protein - ab55692 from Abcam
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Active rat CaMKK full length protein - ab177255 from Abcam
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Human CaMKK full length protein - ab164537 from Abcam
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Human CaMKK protein fragment - ab164538 from Abcam
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CAMKK1 Antibody Blocking Peptide - LS-E22110 from LifeSpan Bioscience
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CAMKK1 Antibody Blocking Peptide - LS-E9248 from LifeSpan Bioscience
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CAMKK1 Antibody Blocking Peptide - LS-E9247 from LifeSpan Bioscience
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Recombinant Human CaMKK alpha Protein - H00084254-P01 from Novus Biologicals
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CaMKK alpha Partial Recombinant Protein - H00084254-Q01 from Novus Biologicals
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CAMKK1-Antibody-Center-Blocking-Peptide - BP7768c from Abgent, a WuXi AppTec company
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CAMKK1-Antibody-N-term-Blocking-Peptide - BP7768a from Abgent, a WuXi AppTec company
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CAMKK1 Blocking Peptide - 33R-2353 from Fitzgerald
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CAMKK1 - H00084254-P01-10 from Acris Antibodies
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CAMKK1 - H00084254-P01-25 from Acris Antibodies
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CAMKK1 - H00084254-Q01-10 from Acris Antibodies
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CAMKK1 - H00084254-Q01-25 from Acris Antibodies
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CAMKK1 - P5507 from Acris Antibodies
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CAMKK1 fusion protein - ag4534 from Proteintech Group
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Recombinant Human CAMKK1 - CAMKK1-26209TH from Creative Biomart
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Recombinant Human CAMKK1, GST-tagged, Active - CAMKK1-269H from Creative Biomart
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Recombinant Human CAMKK1 (Active), GST-tagged - CAMKK1-1374H from Creative Biomart
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Recombinant Human Calcium/calmodulin-dependent protein kinase kinase 1(CAMKK1) - CSB-YP836672HU CSB-EP836672HU CSB-BP836672HU CSB-MP836672HU from Cusabio
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CAMKK1 (transcript variant 3) - TP306389 from Acris Antibodies
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CAMKK1 (transcript variant 1) - TP308102 from Acris Antibodies
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CAMKK1 (transcript variant 2) - TP318931 from Acris Antibodies
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