| Gene Symbol |
MUC2
|
| Entrez Gene |
4583
|
| Alt Symbol |
MLP, MUC-2, SMUC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mucin 2, oligomeric mucus/gel-forming
|
| Other Description |
intestinal mucin-2|mucin 2, intestinal/tracheal|mucin-2|mucin-like protein
|
| Swissprots |
Q14878 Q02817
|
| Accessions |
AAA59875 AAC51519 AAG18515 AAG18516 EAX02421 EAX02422 Q02817 AA527400 AF257167 AAG18517 AW054915 BG982960 BQ340542 CV354692 DV080627 L21998 AAB95295 M22404 AAA36333 M22405 AAA36334 M57417 AAA63229 M86523 AAA59861 M94131 AAA59163 M94132 AAA59164 NM_002457 NP_002448
|
| Function |
Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. {ECO:0000269|PubMed:19432394}.
|
| Subcellular Location |
Secreted. Note=In the intestine, secreted into the inner and outer mucus layers. {ECO:0000250}.
|
| Tissue Specificity |
Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
|
| Top Pathways |
Vibrio cholerae infection, Amoebiasis
|