DOC2B

Gene Symbol DOC2B
Entrez Gene 8447
Alt Symbol DOC2BL
Species Human
Gene Type protein-coding
Description double C2-like domains, beta
Other Description doc2-beta|double C2-like domain-containing protein beta
Swissprots Q14184
Accessions EAW90677 Q14184 AI478508 BC152720 AAI52721 BC153024 AAI53025 BM713588 D70830 BAA11107 DN831650 XM_011535363 XP_011533665 XR_942188 XR_942189 XR_942190 NM_003585 NP_003576
Function Calcium sensor which positively regulates SNARE- dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm. Cytoplasmic granule {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates to the plasma membrane in a calcium-dependent manner. {ECO:0000250}.
Tissue Specificity Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level). {ECO:0000269|PubMed:17548353, ECO:0000269|PubMed:8554557}.

Anti-DOC2B antibody - ab76257 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-DOC2B antibody - ab101764 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-DOC2B antibody - ab88568 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-DOC2B antibody (ab88568) at 1 µg/ml + human kidney tissue lysate at 50 µg

Anti-DOC2B Antibody - LS-C307293 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

DOC2B Antibody - NBP2-13930 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: DOC2B Antibody [NBP2-13930] Staining of human cell line U-251 MG shows positivity in cytoskeleton (microtubules).

Anti-DOC2B antibody produced in mouse - SAB1400312 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-DOC2B, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400312</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~45.9 kDa using human kidney lysate.

Anti-DOC2B antibody produced in rabbit - HPA043168 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-DOC2B:<B>Cat. No. HPA043168</B>: Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.

Anti -DOC2B (Double C2-like Domain-containing Protein beta, Doc2-beta, DOC2BL) - 125981 from USBiological Life Science

Host Mouse
Clonality Polyclonal

Anti-DOC2B Antibody - AC11-0201 from Abcore

Prices $325.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

DOC2B antibody - 70R-16906 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

DOC2B antibody - 20574-1-AP from Acris Antibodies

Prices $270.00
Sizes 150 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of Hela cells, using DOC2B antibody 20574-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

DOC2B antibody - H00008447-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
DOC2B MaxPab polyclonal antibody. Western Blot analysis of DOC2B expression in human kidney.

DOC2B antibody - 20574-1-AP from Proteintech Group

Prices $279.00
Sizes con: 39 μg/150μl
Host Rabbit
Clonality Polyclonal
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 20574-1-AP(DOC2B antibody) at dilution of 1:600

double C2-like domains, beta , Polyclonal Antibody - MBS711580 from MyBioSource

Prices $230.00, $500.00
Sizes 50 µl, 150 µl
Host Rabbit
Clonality Polyclonal

DOC2B Antibody - EPP12396 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
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Anti-DOC2B (aa 360-412) polyclonal antibody - DPABH-04370 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-DOC2B monoclonal antibody - DCABH-11310 from Creative Diagnostics

Host Rabbit
Clonality Monoclonal

DOC2B, Polyclonal Antibody - MBS2522933 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

DOC2B, Polyclonal Antibody - MBS647630 from MyBioSource

Prices $580.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

DOC2B Antibody - H00008447-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DOC2B Antibody [H00008447-B01P] - Analysis of DOC2B expression in human kidney.

DOC2B - A9431 from NeoScientific

Prices $480.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DOC2B Polyclonal Antibody - A9431 from ABclonal

Prices $200.00, $480.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal

DOC2B Antibody - abx124433 from Abbexa

Host Rabbit
Clonality Polyclonal

DOC2B antibody - orb183178 from Biorbyt

Prices $60.00, $128.00, $255.00, $340.00
Sizes 5 μg (Trial size), 20 μg (Trial size), 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

DOC2A antibody - orb30868 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
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