Gene Symbol | IHH |
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Entrez Gene | 3549 |
Alt Symbol | BDA1, HHG2 |
Species | Human |
Gene Type | protein-coding |
Description | indian hedgehog |
Other Description | HHG-2|Indian hedgehog homolog|indian hedgehog protein |
Swissprots | Q8N4B9 Q14623 O43322 B9EGM5 |
Accessions | AAX88920 BAA33523 BAA36285 CAJ18810 CAM31803 EAW70675 Q14623 AI802733 BC034757 AAH34757 BC136587 AAI36588 BC136588 AAI36589 L38517 AAA62178 NM_002181 NP_002172 |
Function | Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21537345}. |
Tissue Specificity | Expressed in embryonic lung, and in adult kidney and liver. |
Top Pathways | Hedgehog signaling pathway |
Ihh (H-12) - sc-271101 from Santa Cruz Biotechnology
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Ihh (E-20) - sc-33939 from Santa Cruz Biotechnology
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Ihh (Y-20) - sc-1189 from Santa Cruz Biotechnology
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Ihh (H-88) - sc-13088 from Santa Cruz Biotechnology
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Ihh (C-15) - sc-1196 from Santa Cruz Biotechnology
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Ihh (I-19) - sc-1782 from Santa Cruz Biotechnology
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Shh (G-5) - sc-373779 from Santa Cruz Biotechnology
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Anti-Ihh antibody - ab39634 from Abcam
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Anti-Ihh antibody - ab184624 from Abcam
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Anti-Ihh antibody - ab124122 from Abcam
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Anti-Ihh antibody - ab134751 from Abcam
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Anti-Ihh antibody [EP1192Y] - ab52919 from Abcam
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Anti-Ihh antibody [MM0606-9L16] - ab135205 from Abcam
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Anti-Ihh antibody - C-terminal - ab135770 from Abcam
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Anti-Ihh antibody - N-terminal - ab80191 from Abcam
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Anti-IHH Antibody (aa397-430) - LS-C344651 from LifeSpan Bioscience
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Anti-IHH Antibody (aa397-430) - LS-C344517 from LifeSpan Bioscience
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Anti-IHH Antibody - LS-C129911 from LifeSpan Bioscience
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Anti-IHH Antibody (aa51-80, AP) - LS-C236538 from LifeSpan Bioscience
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Anti-IHH Antibody (N-Terminus) - LS-C150211 from LifeSpan Bioscience
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Anti-IHH Antibody (aa51-80, Biotin) - LS-C236540 from LifeSpan Bioscience
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Anti-IHH Antibody (aa51-80, APC) - LS-C236539 from LifeSpan Bioscience
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Anti-IHH Antibody (aa51-80, FITC) - LS-C236542 from LifeSpan Bioscience
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Anti-IHH Antibody (aa51-80, PE) - LS-C236543 from LifeSpan Bioscience
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Anti-IHH Antibody (clone 2G9) - LS-C197507 from LifeSpan Bioscience
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