Gene Symbol | GATA1 |
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Entrez Gene | 2623 |
Alt Symbol | ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT |
Species | Human |
Gene Type | protein-coding |
Description | GATA binding protein 1 (globin transcription factor 1) |
Other Description | GATA-binding factor 1|NF-E1 DNA-binding protein|erythroid transcription factor|erythroid transcription factor 1|globin transcription factor 1|nuclear factor, erythroid 1|transcription factor GATA1 |
Swissprots | Q96GB8 P15976 |
Accessions | AGN75067 EAW50749 EAW50750 EAW50751 P15976 AI057349 BC009797 AAH09797 M30601 AAA35885 X17254 CAA35120 XM_011543897 XP_011542199 XM_011543898 XP_011542200 NM_002049 NP_002040 |
Function | Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. {ECO:0000269|PubMed:22235304}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Erythrocytes. {ECO:0000269|PubMed:8524811}. |
GATA-1 CRISPR/Cas9 KO Plasmid (h) - sc-400396 from Santa Cruz Biotechnology
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GATA-1 HDR Plasmid (h) - sc-400396-HDR from Santa Cruz Biotechnology
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GATA-1 Double Nickase Plasmid (h) - sc-400396-NIC from Santa Cruz Biotechnology
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GATA-1 Double Nickase Plasmid (h2) - sc-400396-NIC-2 from Santa Cruz Biotechnology
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GATA-1 CRISPR Activation Plasmid (h) - sc-400396-ACT from Santa Cruz Biotechnology
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GATA-1 CRISPR Activation Plasmid (h2) - sc-400396-ACT-2 from Santa Cruz Biotechnology
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GATA-1 Lentiviral Activation Particles (h) - sc-400396-LAC from Santa Cruz Biotechnology
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GATA-1 Lentiviral Activation Particles (h2) - sc-400396-LAC-2 from Santa Cruz Biotechnology
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GATA-1 siRNA (h) - sc-29330 from Santa Cruz Biotechnology
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GATA-1 shRNA Plasmid (h) - sc-29330-SH from Santa Cruz Biotechnology
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GATA-1 shRNA (h) Lentiviral Particles - sc-29330-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9146 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9146 from Sigma-Aldrich
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GATA1 siRNA (Human) - CRH1739 from Cohesion Biosciences
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GATA-1 RNAi - H00002623-R01 from Novus Biologicals
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GATA1 - MBS826912 from MyBioSource
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GATA-1 CRISPR/Cas9 KO Plasmid (h2) - sc-400396-KO-2 from Santa Cruz Biotechnology
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GATA-1 HDR Plasmid (h2) - sc-400396-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human GATA1 (NM_002049.3) - SHH299526 from Creative biogene
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Human GATA1 siRNA - orb262241 from Biorbyt
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GATA1 shRNA Plasmid (Human) - CHH1739 from Cohesion Biosciences
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GATA1 miRNA 3'UTR clone - MiUTR3H-02969 from Creative biogene
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