| Gene Symbol |
GATA1
|
| Entrez Gene |
2623
|
| Alt Symbol |
ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
GATA binding protein 1 (globin transcription factor 1)
|
| Other Description |
GATA-binding factor 1|NF-E1 DNA-binding protein|erythroid transcription factor|erythroid transcription factor 1|globin transcription factor 1|nuclear factor, erythroid 1|transcription factor GATA1
|
| Swissprots |
Q96GB8 P15976
|
| Accessions |
AGN75067 EAW50749 EAW50750 EAW50751 P15976 AI057349 BC009797 AAH09797 M30601 AAA35885 X17254 CAA35120 XM_011543897 XP_011542199 XM_011543898 XP_011542200 NM_002049 NP_002040
|
| Function |
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. {ECO:0000269|PubMed:22235304}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Erythrocytes. {ECO:0000269|PubMed:8524811}.
|
![Western Blot: GATA1 Overexpression Lysate (Adult Normal) [NBP2-04216] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GATA1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4124_GATA1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04216-img0001.jpg)