Gene Symbol | HHEX |
---|---|
Entrez Gene | 3087 |
Alt Symbol | HEX, HMPH, HOX11L-PEN, PRH, PRHX |
Species | Human |
Gene Type | protein-coding |
Description | hematopoietically expressed homeobox |
Other Description | hematopoietically-expressed homeobox protein HHEX|homeobox protein HEX|homeobox protein PRH|homeobox, hematopoietically expressed|proline-rich homeodomain-containing transcription factor |
Swissprots | B1AQ17 Q03014 Q96CE9 |
Accessions | AAK12833 EAW50087 EAW50088 Q03014 AA810064 AK309463 AK314891 BAG37405 BC014336 AAH14336 BC015110 AAH15110 BC050638 AAH50638 BI823658 BM543214 DB504532 EU446478 ABZ92007 L16499 AAA02988 X67235 CAA47661 Z21533 CAA79730 NM_002729 NP_002720 |
Function | Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Liver and promyelocytic leukemia cell line HL- 60. {ECO:0000269|PubMed:1360645, ECO:0000269|PubMed:8096636, ECO:0000269|PubMed:8103988}. |
Top Pathways | Maturity onset diabetes of the young, Transcriptional misregulation in cancer |
Human Hex full length protein - ab132363 from Abcam
|
||||||||||
Human Hex full length protein - ab134846 from Abcam
|
||||||||||
Human Hex full length protein - ab167885 from Abcam
|
||||||||||
Human Hex peptide - ab28465 from Abcam
|
||||||||||
HHEX / HEX Antibody Blocking Peptide - LS-E5902 from LifeSpan Bioscience
|
||||||||||
HHEX / HEX Antibody Blocking Peptide - LS-E13221 from LifeSpan Bioscience
|
||||||||||
HHEX / HEX Antibody Blocking Peptide - LS-E13222 from LifeSpan Bioscience
|
||||||||||
HHEX / HEX Antibody Blocking Peptide - LS-E21220 from LifeSpan Bioscience
|
||||||||||
HHEX Recombinant Protein - H00003087-P01 from Novus Biologicals
|
||||||||||
Recombinant Human HHEX Protein - NBP2-23108 from Novus Biologicals
|
||||||||||
HHEX-Antibody-C-term-Blocking-Peptide - BP18467b from Abgent, a WuXi AppTec company
|
||||||||||
HHEX Protein Lysate (APL10253) - APL10253 from Aviva Systems Biology
|
||||||||||
Human HHEX protein - orb191324 from Biorbyt
|
||||||||||
HHEX protein (His tag) - 80R-2945 from Fitzgerald
|
||||||||||
HHEX / PRH (1-270, His-tag) - AR51063PU-N from Acris Antibodies
|
||||||||||
HHEX / PRH (1-270, His-tag) - AR51063PU-S from Acris Antibodies
|
||||||||||
HHEX / PRH - H00003087-P01-10 from Acris Antibodies
|
||||||||||
HHEX / PRH - H00003087-P01-25 from Acris Antibodies
|
||||||||||
HHEX, 1-270aa, Human, His tag, E.coli - 01-P2239 from ARP American Research Products
|
||||||||||
HHEX fusion protein - ag13429 from Proteintech Group
|
||||||||||
HHEX fusion protein - Ag13423 from Proteintech Group
|
||||||||||
Recombinant Human HHEX, His-tagged - HHEX-15883H from Creative Biomart
|
||||||||||
HHEX, 1-270aa, Human, His tag, E.coli - ATGP2239 from ATGen
|
||||||||||
HHEX / PRH - TP304815 from Acris Antibodies
|
||||||||||
HEX, Peptide - MBS659491 from MyBioSource
|