Gene Symbol | Scd1 |
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Entrez Gene | 20249 |
Alt Symbol | AA589638, AI265570, Scd, Scd-1, ab |
Species | Mouse |
Gene Type | protein-coding |
Description | stearoyl-Coenzyme A desaturase 1 |
Other Description | acyl-CoA desaturase 1|asebia|delta(9)-desaturase 1|delta-9 desaturase 1|fatty acid desaturase 1|stearoyl-CoA desaturase 1 |
Swissprots | Q922I6 P13516 |
Accessions | AAA40103 EDL41930 P13516 AA881780 AF509567 AAM34744 AF509570 AAM34747 AK012370 AK078704 AK135642 BAE22598 AK142630 BAE25137 AK148103 BAE28345 AK163960 BC007474 AAH07474 BC055453 AAH55453 BC114387 BC114388 BC114417 BQ885468 BU053011 CD544724 CT010171 CAJ18379 CT010332 CAJ18540 NM_009127 NP_033153 |
Function | Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:16275639}; Multi-pass membrane protein {ECO:0000269|PubMed:16275639}. |
Top Pathways | PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism |
SCD1 CRISPR/Cas9 KO Plasmid (m) - sc-422809 from Santa Cruz Biotechnology
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SCD1 HDR Plasmid (m) - sc-422809-HDR from Santa Cruz Biotechnology
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SCD1 Double Nickase Plasmid (m) - sc-422809-NIC from Santa Cruz Biotechnology
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SCD1 Double Nickase Plasmid (m2) - sc-422809-NIC-2 from Santa Cruz Biotechnology
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SCD1 CRISPR Activation Plasmid (m) - sc-422809-ACT from Santa Cruz Biotechnology
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SCD1 CRISPR Activation Plasmid (m2) - sc-422809-ACT-2 from Santa Cruz Biotechnology
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SCD1 Lentiviral Activation Particles (m) - sc-422809-LAC from Santa Cruz Biotechnology
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SCD1 Lentiviral Activation Particles (m2) - sc-422809-LAC-2 from Santa Cruz Biotechnology
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SCD1 siRNA (m) - sc-36465 from Santa Cruz Biotechnology
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SCD1 shRNA Plasmid (m) - sc-36465-SH from Santa Cruz Biotechnology
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SCD1 shRNA (m) Lentiviral Particles - sc-36465-V from Santa Cruz Biotechnology
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SCD1/2/3/4 siRNA (m) - sc-63288 from Santa Cruz Biotechnology
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SCD1/2/3/4 shRNA Plasmid (m) - sc-63288-SH from Santa Cruz Biotechnology
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SCD1/2/3/4 shRNA (m) Lentiviral Particles - sc-63288-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU023031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN40753 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND40753 from Sigma-Aldrich
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SCD1 siRNA (Mouse) - CRM3601 from Cohesion Biosciences
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SCD1 - MBS8209529 from MyBioSource
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shRNA set against Mouse Scd1 (NM_009127.4) - SHH402480 from Creative biogene
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Mouse SCD1 siRNA - orb283077 from Biorbyt
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SCD1 shRNA Plasmid (Mouse) - CHM3601 from Cohesion Biosciences
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