| Gene Symbol |
Scd1
|
| Entrez Gene |
20249
|
| Alt Symbol |
AA589638, AI265570, Scd, Scd-1, ab
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
stearoyl-Coenzyme A desaturase 1
|
| Other Description |
acyl-CoA desaturase 1|asebia|delta(9)-desaturase 1|delta-9 desaturase 1|fatty acid desaturase 1|stearoyl-CoA desaturase 1
|
| Swissprots |
Q922I6 P13516
|
| Accessions |
AAA40103 EDL41930 P13516 AA881780 AF509567 AAM34744 AF509570 AAM34747 AK012370 AK078704 AK135642 BAE22598 AK142630 BAE25137 AK148103 BAE28345 AK163960 BC007474 AAH07474 BC055453 AAH55453 BC114387 BC114388 BC114417 BQ885468 BU053011 CD544724 CT010171 CAJ18379 CT010332 CAJ18540 NM_009127 NP_033153
|
| Function |
Terminal component of the liver microsomal stearyl-CoA desaturase system, that utilizes O(2) and electrons from reduced cytochrome b5 to catalyze the insertion of a double bond into a spectrum of fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:16275639}; Multi-pass membrane protein {ECO:0000269|PubMed:16275639}.
|
| Top Pathways |
PPAR signaling pathway, AMPK signaling pathway, Biosynthesis of unsaturated fatty acids, Fatty acid metabolism
|