Gene Symbol | CMAS |
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Entrez Gene | 55907 |
Alt Symbol | CSS |
Species | Human |
Gene Type | protein-coding |
Description | cytidine monophosphate N-acetylneuraminic acid synthetase |
Other Description | CMP-N-acetylneuraminic acid synthase|CMP-N-acetylneuraminic acid synthetase|CMP-Neu5Ac synthetase|CMP-NeuNAc synthase|CMP-NeuNAc synthetase|CMP-sialic acid synthetase|N-acylneuraminate cytidylyltransferase|cytidine 5'-monophosphate N-acetylneuraminic acid synthetase |
Swissprots | Q8NFW8 Q96AX5 Q9NQZ0 |
Accessions | EAW96464 EAW96465 EAW96466 Q8NFW8 AF271388 AAF76203 AF397212 AAM90580 AK022927 BAB14311 AK124990 AK222981 BAD96701 AL832975 CAH56346 BC016609 AAH16609 BM671960 DA344740 DB527942 JF432877 ADZ16094 XR_931313 NM_018686 NP_061156 |
Function | Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11602804}. |
Tissue Specificity | Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen. {ECO:0000269|PubMed:11602804}. |
Top Pathways | Amino sugar and nucleotide sugar metabolism |
CMAS CRISPR/Cas9 KO Plasmid (h) - sc-409575 from Santa Cruz Biotechnology
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CMAS HDR Plasmid (h) - sc-409575-HDR from Santa Cruz Biotechnology
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CMAS Double Nickase Plasmid (h) - sc-409575-NIC from Santa Cruz Biotechnology
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CMAS Double Nickase Plasmid (h2) - sc-409575-NIC-2 from Santa Cruz Biotechnology
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CMAS CRISPR Activation Plasmid (h) - sc-409575-ACT from Santa Cruz Biotechnology
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CMAS CRISPR Activation Plasmid (h2) - sc-409575-ACT-2 from Santa Cruz Biotechnology
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CMAS Lentiviral Activation Particles (h) - sc-409575-LAC from Santa Cruz Biotechnology
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CMAS Lentiviral Activation Particles (h2) - sc-409575-LAC-2 from Santa Cruz Biotechnology
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CMAS siRNA (h) - sc-95844 from Santa Cruz Biotechnology
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CMAS shRNA Plasmid (h) - sc-95844-SH from Santa Cruz Biotechnology
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CMAS shRNA (h) Lentiviral Particles - sc-95844-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU069341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6280 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6280 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02873 from Sigma-Aldrich
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CMAS siRNA (Human) - CRJ1006 from Cohesion Biosciences
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CMAS RNAi - H00055907-R01 from Novus Biologicals
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CMAS - MBS8218298 from MyBioSource
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CMAS shRNA Plasmid (Human) - CHJ1006 from Cohesion Biosciences
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CMAS miRNA 3'UTR clone - MiUTR3H-05856 from Creative biogene
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