| Gene Symbol |
CMAS
|
| Entrez Gene |
55907
|
| Alt Symbol |
CSS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytidine monophosphate N-acetylneuraminic acid synthetase
|
| Other Description |
CMP-N-acetylneuraminic acid synthase|CMP-N-acetylneuraminic acid synthetase|CMP-Neu5Ac synthetase|CMP-NeuNAc synthase|CMP-NeuNAc synthetase|CMP-sialic acid synthetase|N-acylneuraminate cytidylyltransferase|cytidine 5'-monophosphate N-acetylneuraminic acid synthetase
|
| Swissprots |
Q8NFW8 Q96AX5 Q9NQZ0
|
| Accessions |
EAW96464 EAW96465 EAW96466 Q8NFW8 AF271388 AAF76203 AF397212 AAM90580 AK022927 BAB14311 AK124990 AK222981 BAD96701 AL832975 CAH56346 BC016609 AAH16609 BM671960 DA344740 DB527942 JF432877 ADZ16094 XR_931313 NM_018686 NP_061156
|
| Function |
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN).
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11602804}.
|
| Tissue Specificity |
Ubiquitously expressed. Expressed in pancreas, kidney, liver, skeletal muscle, lung, placenta, brain, heart, colon, PBL, small intestine, ovary, testis, prostate, thymus and spleen. {ECO:0000269|PubMed:11602804}.
|
| Top Pathways |
Amino sugar and nucleotide sugar metabolism
|