| Gene Symbol |
TTC19
|
| Entrez Gene |
54902
|
| Alt Symbol |
2010204O13Rik, MC3DN2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tetratricopeptide repeat domain 19
|
| Other Description |
TPR repeat protein 19|tetratricopeptide repeat protein 19, mitochondrial
|
| Swissprots |
Q9NXB2 A8MZ52 Q9H6G3 Q7L3U8 B4DN65 B3KP62 Q2M248 Q6DKK2
|
| Accessions |
EAX04490 EAX04491 Q6DKK2 AK000350 BAA91103 AK025958 BAB15296 AK055780 BAG51574 AK056878 BAG51820 AK094819 BAG52935 AK297783 BAG60127 AL832412 AW083291 BC003058 BC011698 AAH11698 BC073796 AAH73796 BC105128 AAI05129 BC112107 AAI12108 CA417932 XM_011523950 XP_011522252 NM_001271420 NP_001258349 NM_017775 NP_060245
|
| Function |
Mitochondrial protein required for formation of the mitochondrial complex III (PubMed:21278747). May also be required for the abcission step in cytokinesis, possibly regulating the ESCRT-III complex via its interaction with CHMP4B (PubMed:20208530). However, the involvement in cytokinesis requires additional experimental evidence. {ECO:0000269|PubMed:20208530, ECO:0000269|PubMed:21278747}.
|
| Subcellular Location |
Mitochondrion inner membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=According to some authors, localizes to the centrosome during all stages of the cell cycle and is recruited to the midbody during cytokinesis (PubMed:20208530). However, the midbody localization could not be confirmed by others (PubMed:21278747). {ECO:0000269|PubMed:20208530, ECO:0000269|PubMed:21278747}.
|