POLR3D

Gene Symbol POLR3D
Entrez Gene 661
Alt Symbol BN51T, RPC4, RPC53, TSBN51
Species Human
Gene Type protein-coding
Description polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Other Description BN51 (BHK21) temperature sensitivity complementing|DNA-directed RNA polymerase III 47 kDa polypeptide|DNA-directed RNA polymerase III subunit D|DNA-directed RNA polymerase III subunit RPC4|RNA polymerase III 47 kDa subunit|RNA polymerase III subunit C4|RPC53 homolog|temperature sensitive complementation, cell cycle specific, tsBN51
Swissprots Q9BPV7 Q9BXB3 Q6FI28 P05423 Q9BPZ1
Accessions AAA72377 AAD29429 EAW63689 EAW63690 EAW63691 EAW63692 P05423 AF346574 AAK15371 AK026588 AK125346 AK295725 BAG58566 AY092086 AAM18216 BC000516 BC002603 AAH02603 BC003039 BC004484 AAH04484 BQ006609 BX537545 CR536509 CAG38747 CR541803 CAG46602 HQ447310 ADQ31797 M17754 AAA51838 XM_011544629 XP_011542931 XR_949463 NM_001722 NP_001713
Function DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity). {ECO:0000250}.
Subcellular Location Nucleus.
Top Pathways Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

POLR3D (C-14) - sc-87361 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

POLR3D (N-14) - sc-87362 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-POLR3D antibody - ab86786 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling POLR3D with ab86786 at 1/1000 (0.2µg/ml). Detection: DAB.

Anti-POLR3D antibody - ab138071 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-POLR3D antibody (ab138071) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-POLR3D antibody - ab86785 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-POLR3D antibody (ab86785) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-POLR3D antibody - ab114991 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Staining of Human POLR3D in a Formalin/PFA-fixed paraffin-embedded section of Human Prostate Carcinoma using ab114991 at a dilution of 1/100.

Anti-POLR3D Antibody (aa127-156, AP) - LS-C266701 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa127-156, APC) - LS-C266702 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa127-156, Biotin) - LS-C266703 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa127-156, Azide-free, HRP) - LS-C266705 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa127-156, PE) - LS-C266706 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa126-156) - LS-C324176 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-POLR3D Antibody (aa265-314) - LS-C200612 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using RPC4 antibody.

Anti-POLR3D Antibody (aa281-330) - LS-C119919 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from MCF-7 cells, using RPC4 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-POLR3D Antibody (Asn314) - LS-C177829 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of POLR3D (N314) pAb in extracts from MCF-7 cells.

Anti-POLR3D Antibody (clone 4E6) - LS-C196766 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4E6
Detection limit for recombinant GST tagged POLR3D is approximately 0.3 ng/ml as a capture antibody.

Anti-POLR3D Antibody (aa127-156) - LS-C163857 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
POLR3D Antibody western blot of 293 cell line lysates (35 ug/lane). The POLR3D antibody detected the POLR3D protein (arrow).

Anti-POLR3D Antibody (aa175-225) - LS-C286868 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human POLR3D by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-POLR3D used at a dilution of 1:100.

Anti-POLR3D Antibody (aa175-225) - LS-C289046 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human POLR3D by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-POLR3D used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.

Anti-POLR3D Antibody (aa348-398) - LS-C289045 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human POLR3D by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-POLR3D antibody used for WB at 0.1 ug/ml Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-POLR3D Antibody (aa127-156, FITC) - LS-C266704 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

POLR3D Antibody - NBP1-28737 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: POLR3D Antibody [NBP1-28737] - Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-POLR3D antibody NBP1-28737 used for WB at 0.04 ug/ml (A) and 1 ug/ml (B) and used for IP at 10 ug/mg lysate. POLR3D was also immunoprecipitated by rabbit anti-POLR3D antibody NBP1-28726, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 3 seconds (B).

POLR3D Antibody - NBP1-68475 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: POLR3D Antibody [NBP1-68475] - Analysis of extracts from MCF-7 cells, using POLR3D Antibody. The lane on the right is treated with the synthesized peptide.

POLR3D Antibody - NBP1-51360 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: POLR3D Antibody [NBP1-51360] - Analysis of POLR3D (N314) pAb in extracts from MCF-7 cells.

POLR3D Antibody - H00000661-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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