| Gene Symbol |
HTR3E
|
| Entrez Gene |
285242
|
| Alt Symbol |
5-HT3-E, 5-HT3E, 5-HT3c1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
|
| Other Description |
5-hydroxytryptamine (serotonin) receptor 3, family member E|5-hydroxytryptamine receptor 3 subunit E|5-hydroxytryptamine receptor 3E
|
| Swissprots |
Q6V706 Q6V707 E9PGF1 A8IKD7 Q7Z6B2 Q495G3 A5X5Y0 Q495G1
|
| Accessions |
A5X5Y0 EAW78304 AY159813 AAO38167 AY349352 AAQ93476 AY349353 AAQ93477 BC101182 AAI01183 BC101183 AAI01184 BC101184 BC101185 AAI01186 DQ644022 ABG35128 EU165354 ABW05298 NM_001256613 NP_001243542 NM_001256614 NP_001243543 NM_182589 NP_872395 NM_198313 NP_938055 NM_198314 NP_938056
|
| Function |
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:17392525, ECO:0000269|PubMed:19012743}; Multi-pass membrane protein {ECO:0000269|PubMed:17392525, ECO:0000269|PubMed:19012743}. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
|
| Tissue Specificity |
Expressed in adult colon and intestine. {ECO:0000269|PubMed:12801637, ECO:0000269|PubMed:14597179}.
|