Gene Symbol | Cad |
---|---|
Entrez Gene | 69719 |
Alt Symbol | 2410008J01Rik, AU018859, Cpad |
Species | Mouse |
Gene Type | protein-coding |
Description | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
Other Description | CAD protein |
Swissprots | B2RQC6 B7ZN27 |
Accessions | B2RQC6 EDL37327 EDL37328 EDL37329 EDL37330 EDL37331 AF053339 AAC78296 AK010453 BAB26952 BC026620 BC043325 AAH43325 BC053097 AAH53097 BC060119 BC060717 AAH60717 BC137856 AAI37857 BC144972 AAI44973 BC144973 CJ104747 XM_006504091 XP_006504154 XM_006504092 XP_006504155 NM_001289522 NP_001276451 NM_001289523 NP_001276452 NM_023525 NP_076014 |
Function | This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth. {ECO:0000250}. |
Top Pathways | Alanine, aspartate and glutamate metabolism, Pyrimidine metabolism |
CPS2 CRISPR/Cas9 KO Plasmid (m) - sc-427509 from Santa Cruz Biotechnology
|
||||||||
CPS2 HDR Plasmid (m) - sc-427509-HDR from Santa Cruz Biotechnology
|
||||||||
CPS2 Double Nickase Plasmid (m) - sc-427509-NIC from Santa Cruz Biotechnology
|
||||||||
CPS2 Double Nickase Plasmid (m2) - sc-427509-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CPS2 CRISPR Activation Plasmid (m) - sc-427509-ACT from Santa Cruz Biotechnology
|
||||||||
CPS2 CRISPR Activation Plasmid (m2) - sc-427509-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CPS2 Lentiviral Activation Particles (m) - sc-427509-LAC from Santa Cruz Biotechnology
|
||||||||
CPS2 Lentiviral Activation Particles (m2) - sc-427509-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CPS2 siRNA (m) - sc-41458 from Santa Cruz Biotechnology
|
||||||||
CPS2 shRNA Plasmid (m) - sc-41458-SH from Santa Cruz Biotechnology
|
||||||||
CPS2 shRNA (m) Lentiviral Particles - sc-41458-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EMU004181 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN27895 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND27895 from Sigma-Aldrich
|
||||||||
CAD siRNA (Mouse) - CRM8058 from Cohesion Biosciences
|
||||||||
CAD - MBS8208077 from MyBioSource
|
||||||||
shRNA set against Mouse CAD (NM_023525.1) - SHH253577 from Creative biogene
|
||||||||
shRNA set against Mouse Cad(NM_023525.1) - SHG132775 from Creative biogene
|
||||||||
CAD shRNA Plasmid (Mouse) - CHM8058 from Cohesion Biosciences
|
||||||||
CAD miRNA 3'UTR clone - MiUTR1M-02455 from Creative biogene
|