| Gene Symbol |
Cad
|
| Entrez Gene |
69719
|
| Alt Symbol |
2410008J01Rik, AU018859, Cpad
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
|
| Other Description |
CAD protein
|
| Swissprots |
B2RQC6 B7ZN27
|
| Accessions |
B2RQC6 EDL37327 EDL37328 EDL37329 EDL37330 EDL37331 AF053339 AAC78296 AK010453 BAB26952 BC026620 BC043325 AAH43325 BC053097 AAH53097 BC060119 BC060717 AAH60717 BC137856 AAI37857 BC144972 AAI44973 BC144973 CJ104747 XM_006504091 XP_006504154 XM_006504092 XP_006504155 NM_001289522 NP_001276451 NM_001289523 NP_001276452 NM_023525 NP_076014
|
| Function |
This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Cytosolic and unphosphorylated in resting cells, translocates to the nucleus in response to EGF stimulation, nuclear import promotes optimal cell growth. {ECO:0000250}.
|
| Top Pathways |
Alanine, aspartate and glutamate metabolism, Pyrimidine metabolism
|