SLC9A3

Gene Symbol SLC9A3
Entrez Gene 6550
Alt Symbol NHE3
Species Human
Gene Type protein-coding
Description solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Other Description NHE-3|Na(+)/H(+) exchanger 3|sodium/hydrogen exchanger 3|solute carrier family 9 (sodium/hydrogen exchanger)|solute carrier family 9 (sodium/hydrogen exchanger), member 3|solute carrier family 9 member 3
Swissprots Q3MIW3 B7ZKR2 E9PF67 P48764
Accessions AAM53435 EAW51006 EAW51007 P48764 BC011555 BC101669 AAI01670 BC101671 AAI01672 BC143328 AAI43329 BP270851 S83545 AAB50819 U28043 AAB48990 XM_011514095 XP_011512397 XM_011514096 XP_011512398 XM_011514097 XP_011512399 XM_011514098 XP_011512400 NM_001284351 NP_001271280 NM_004174 NP_004165
Function Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Subcellular Location Apical cell membrane {ECO:0000269|PubMed:19088451}; Multi-pass membrane protein {ECO:0000269|PubMed:19088451}. Note=In intestinal epithelial cells, localizes to the ileal brush border. Phosphorylation at Ser-663 by SGK1 is associated with increased abundance at the cell membrane.
Top Pathways Proximal tubule bicarbonate reclamation, Protein digestion and absorption, Bile secretion, Mineral absorption

NHE-3 CRISPR/Cas9 KO Plasmid (h) - sc-401420 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 HDR Plasmid (h) - sc-401420-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 Double Nickase Plasmid (h) - sc-401420-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 Double Nickase Plasmid (h2) - sc-401420-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 CRISPR Activation Plasmid (h) - sc-401420-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 CRISPR Activation Plasmid (h2) - sc-401420-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 Lentiviral Activation Particles (h) - sc-401420-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 Lentiviral Activation Particles (h2) - sc-401420-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NHE-3 siRNA (h) - sc-36059 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NHE-3 shRNA Plasmid (h) - sc-36059-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NHE-3 shRNA (h) Lentiviral Particles - sc-36059-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NHE3/SLC9A3 RNAi - H00006550-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU149191 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19702 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19702 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SLC9A3 siRNA (Human) - CRH4442 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC9A3 - MBS8203758 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLC9A3 (NM_004174.2) - SHH412296 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLC9A3 siRNA - orb264944 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC9A3 shRNA Plasmid (Human) - CHH4442 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC9A3 miRNA 3'UTR clone - MiUTR3H-02109 from Creative biogene

Species Reactivities Human
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