ITGAV

Gene Symbol ITGAV
Entrez Gene 3685
Alt Symbol CD51, MSK8, VNRA, VTNR
Species Human
Gene Type protein-coding
Description integrin, alpha V
Other Description antigen identified by monoclonal antibody L230|integrin alpha-V|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|vitronectin receptor subunit alpha
Swissprots B0LPF4 P06756 A0AV67 Q59EB7 D3DPG8 B7Z883 B7ZLX0 Q53SK4 E7EWZ6 Q6LD15
Accessions AAA20462 AAA61631 AAG03000 AAY24257 ABY87533 AGC09592 EAX10933 EAX10934 P06756 AB209894 BAD93131 AK302550 BAG63819 AK302990 BAH13869 AK309711 BC047454 BC072686 BC126231 AAI26232 BC136442 AAI36443 BC144100 AAI44101 BQ101180 BQ129340 CB962576 CN409399 DA736912 EF560727 ABQ59037 M14648 AAA36808 N83286 XM_006712513 XP_006712576 NM_001144999 NP_001138471 NM_001145000 NP_001138472 NM_002210 NP_002201
Function The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Proteoglycans in cancer, PI3K-Akt signaling pathway, Phagosome, Focal adhesion, Dilated cardiomyopathy

Integrin αV CRISPR/Cas9 KO Plasmid (h) - sc-400506 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV HDR Plasmid (h) - sc-400506-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV Double Nickase Plasmid (h) - sc-400506-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV Double Nickase Plasmid (h2) - sc-400506-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV CRISPR Activation Plasmid (h) - sc-400506-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV CRISPR Activation Plasmid (h2) - sc-400506-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV Lentiviral Activation Particles (h) - sc-400506-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV Lentiviral Activation Particles (h2) - sc-400506-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Integrin αV siRNA (h) - sc-29373 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin αV shRNA Plasmid (h) - sc-29373-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Integrin αV shRNA (h) Lentiviral Particles - sc-29373-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU002301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1029 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1029 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ITGAV siRNA (Human) - CRH2475 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Integrin alpha V/CD51 RNAi - H00003685-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ITGAV - MBS8216591 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ITGAV (NM_002210.3) - SHH321317 from Creative biogene

Category siRNA
Species Reactivities Human

Human ITGAV siRNA - orb262977 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ITGAV shRNA Plasmid (Human) - CHH2475 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ITGAV miRNA 3'UTR clone - MiUTR4H-TG04599 from Creative biogene

Species Reactivities Human
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