ITGAV

Gene Symbol ITGAV
Entrez Gene 3685
Alt Symbol CD51, MSK8, VNRA, VTNR
Species Human
Gene Type protein-coding
Description integrin, alpha V
Other Description antigen identified by monoclonal antibody L230|integrin alpha-V|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|vitronectin receptor subunit alpha
Swissprots B0LPF4 P06756 A0AV67 Q59EB7 D3DPG8 B7Z883 B7ZLX0 Q53SK4 E7EWZ6 Q6LD15
Accessions AAA20462 AAA61631 AAG03000 AAY24257 ABY87533 AGC09592 EAX10933 EAX10934 P06756 AB209894 BAD93131 AK302550 BAG63819 AK302990 BAH13869 AK309711 BC047454 BC072686 BC126231 AAI26232 BC136442 AAI36443 BC144100 AAI44101 BQ101180 BQ129340 CB962576 CN409399 DA736912 EF560727 ABQ59037 M14648 AAA36808 N83286 XM_006712513 XP_006712576 NM_001144999 NP_001138471 NM_001145000 NP_001138472 NM_002210 NP_002201
Function The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Subcellular Location Membrane; Single-pass type I membrane protein.
Top Pathways Proteoglycans in cancer, PI3K-Akt signaling pathway, Phagosome, Focal adhesion, Dilated cardiomyopathy

Integrin αV Antibody - 4711 from Cell Signaling Technology

Prices $99.00, $246.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from A549 and C6 cells using Integrin αV Antibody.

Integrin αV (H-2) - sc-376156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αV (H-2): sc-376156. Immunofluorescence staining of methanol-fixed HeLa cells membrane and focal adhesion site localization.

Integrin αV (P2W7) - sc-9969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αV (P2W7) PE: sc-9969 PE. FCM analysis of human peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

Integrin αV (H-75) - sc-10719 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Integrin αV (H-75): sc-10719. Western blot analysis of Integrin αV expression in THP-1 whole cell lysate.

Integrin αV (T-20) - sc-6618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Integrin V (T-20): sc-6618. Western blot analysis of Integrin αV expression in A549 (A) and HUV-EC-C (B) whole cell lysates.

Integrin αV (N-19) - sc-6616 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Integrin αV (2Q888) - sc-71451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Integrin αV (13C2) - sc-53360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αV (13C2): sc-53360. Indirect FCM analysis of human peripheral blood leukocytes stained with Integrin αV (13C2), followed by PE-conjugated goat anti-mouse IgG: sc-3738. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-3877.

Integrin αV (NKI-M9) - sc-59844 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Integrin αV/β5 (P1F76) - sc-13588 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Integrin αV/β5 (P1F76): sc-13588. Immunofluorescence staining of methanol-fixed THP-1 cells showing membrane and cell junction localization.

Integrin αV/β5 (P1F6) - sc-81632 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

Anti-CD51 + CD61 antibody [23C6] - ab20143 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 23C6

Anti-CD51 + CD61 antibody [23C6] (Biotin) - ab134488 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 23C6
Flow cytometric analysis of total viable M21 cells labelling Human CD51+CD61 with ab134488 (filled histogram) at 0.5 µg or with 0.5 µg of Mouse IgG1 kappa Isotype Control (open histogram), followed by Streptavidin PE.

Anti-CD51 + CD61 antibody [23C6] (FITC) - ab93513 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 23C6
ab93513 at 5µl/test staining CD51 + CD61 in M21 cells (blue histogram) or FITC mouse IgG1, k Isotype control (green histogram). Total viable cells were used for analysis.

Anti-CD51 antibody - ab112487 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CD51 antibody (ab112487)Lane 1 : Rat spleen tissue lysateLane 2 : Rat pancreas tissue lysateLane 3 : Rat brain tissue lysateLane 4 : Rat liver tissue lysateLane 5 : MM231 whole cell lysateLane 6 : HeLa whole cell lysateLane 7 : CEM whole cell lysateLane 8 : Colo320 whole cell lysate

Anti-CD51 antibody [23C6] - Low endotoxin, Azide free - ab185741 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 23C6
Flow cytometric analysis of platelets labeling CD51 with 0.5 µg ab185741 (filled histogram) or 0.5 µg mouse IgG1 kappa Isotype Control (open histogram). Detection utilised anti-mouse IgG FITC.

Anti-CD51 antibody [HCD51] - ab125684 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HCD51
Human melanoma (total viable cell number is 1x106/100 µl) were stained by 5 µg of ab125684 at RT for 30 min followed by FITC conjugated Goat anti Mouse IgG.

Anti-CD51 antibody [NKI-M9 (former PAF2a)] - ab182900 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NKI-M9 (former PAF2a)

Anti-Integrin alpha V + beta 6 antibody [10D5] - ab77906 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 10D5

Anti-Integrin alpha V + beta 6 antibody [avß6 53a.2] - ab97588 from Abcam

Prices $378.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone avß6 53a.2
Flow cytometry analysis of BT-20 breast carcinoma cells staining Integrin alpha V + beta 6 with ab97588. Cells were cultured in serum free DMEM medium before being trypsinized from the cell culture flask. The sample was incubated with the primary antibody (5 µg/ml in serum free medium) for 1 hour at 4°C. An AlexaFluor®488-conjugated donkey anti-rat IgG polyclonal (1/250) was used as the secondary antibody.Gating Strategy: Live cellsSee Abreview

Anti-Integrin alpha V antibody - ab117611 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab117611, at 5 µg/ml, staining Integrin alpha V in Formalin-fixed, Paraffin-embedded Human Thyroid tissue by Immunohistochemistry.

Anti-Integrin alpha V antibody - ab92797 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Integrin alpha V antibody (ab92797) at 1/500 dilutionLane 1 : extracts from A549 cells, treated with etoposide (25µM, 1hour)Lane 2 : extracts from A549 cells, treated with etoposide (25µM, 1hour) with immunizing peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-Integrin alpha V antibody - ab55991 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Integrin alpha V antibody [13C2] - ab6133 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 13C2

Anti-Integrin alpha V antibody [13C2] (Phycoerythrin) - ab82530 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 13C2
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