Gene Symbol | SEC11A |
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Entrez Gene | 23478 |
Alt Symbol | 1810012E07Rik, SEC11L1, SPC18, SPCS4A, sid2895 |
Species | Human |
Gene Type | protein-coding |
Description | SEC11 homolog A (S. cerevisiae) |
Other Description | SEC11-like protein 1|SPase 18 kDa subunit|endopeptidase SP18|microsomal signal peptidase 18 kDa subunit|signal peptidase complex (18kD)|signal peptidase complex catalytic subunit SEC11A |
Swissprots | H0YK83 Q53FQ8 H0YK72 P67812 B4DUL4 B2RAD7 |
Accessions | EAX01952 EAX01953 EAX01954 EAX01955 EAX01956 P67812 AA151795 AB209437 BAD92674 AF061737 AAD17526 AF087906 AAP97204 AF090315 AAC36354 AF108945 AAD19640 AI051931 AK223224 BAD96944 AK300693 BAG62376 AK314146 BAG36834 BC000359 AAH00359 BC014508 AAH14508 BF920344 BG703137 BI545042 BM763471 BM904189 BM985046 BP370483 BU540274 CD356160 CF455691 CR457127 CAG33408 CT001736 DA963119 DC360846 DQ891826 ABM82752 FN058159 HY170714 NM_001271918 NP_001258847 NM_001271919 NP_001258848 NM_001271920 NP_001258849 NM_001271921 NP_001258850 NM_001271922 NP_001258851 NM_014300 NP_055115 NR_073518 |
Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
Subcellular Location | Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
Top Pathways | Protein export |
SEC11A CRISPR/Cas9 KO Plasmid (h) - sc-411746 from Santa Cruz Biotechnology
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SEC11A HDR Plasmid (h) - sc-411746-HDR from Santa Cruz Biotechnology
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SEC11A Double Nickase Plasmid (h) - sc-411746-NIC from Santa Cruz Biotechnology
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SEC11A Double Nickase Plasmid (h2) - sc-411746-NIC-2 from Santa Cruz Biotechnology
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SEC11A CRISPR Activation Plasmid (h) - sc-411746-ACT from Santa Cruz Biotechnology
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SEC11A CRISPR Activation Plasmid (h2) - sc-411746-ACT-2 from Santa Cruz Biotechnology
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SEC11A Lentiviral Activation Particles (h) - sc-411746-LAC from Santa Cruz Biotechnology
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SEC11A Lentiviral Activation Particles (h2) - sc-411746-LAC-2 from Santa Cruz Biotechnology
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SEC11A siRNA (h) - sc-89989 from Santa Cruz Biotechnology
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SEC11A shRNA Plasmid (h) - sc-89989-SH from Santa Cruz Biotechnology
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SEC11A shRNA (h) Lentiviral Particles - sc-89989-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU105801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19017 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19017 from Sigma-Aldrich
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SEC11A siRNA (Human) - CRH8296 from Cohesion Biosciences
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SEC11A - MBS8208268 from MyBioSource
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shRNA set against Human SEC11A (NM_014300.2) - SHH403608 from Creative biogene
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shRNA set against Human SEC11A(NM_014300.2) - SHR211344 from Creative biogene
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Human SEC11A siRNA - orb268798 from Biorbyt
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SEC11A shRNA Plasmid (Human) - CHH8296 from Cohesion Biosciences
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SEC11A miRNA 3'UTR clone - MiUTR1H-09225 from Creative biogene
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