| Gene Symbol |
SEC11A
|
| Entrez Gene |
23478
|
| Alt Symbol |
1810012E07Rik, SEC11L1, SPC18, SPCS4A, sid2895
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SEC11 homolog A (S. cerevisiae)
|
| Other Description |
SEC11-like protein 1|SPase 18 kDa subunit|endopeptidase SP18|microsomal signal peptidase 18 kDa subunit|signal peptidase complex (18kD)|signal peptidase complex catalytic subunit SEC11A
|
| Swissprots |
H0YK83 Q53FQ8 H0YK72 P67812 B4DUL4 B2RAD7
|
| Accessions |
EAX01952 EAX01953 EAX01954 EAX01955 EAX01956 P67812 AA151795 AB209437 BAD92674 AF061737 AAD17526 AF087906 AAP97204 AF090315 AAC36354 AF108945 AAD19640 AI051931 AK223224 BAD96944 AK300693 BAG62376 AK314146 BAG36834 BC000359 AAH00359 BC014508 AAH14508 BF920344 BG703137 BI545042 BM763471 BM904189 BM985046 BP370483 BU540274 CD356160 CF455691 CR457127 CAG33408 CT001736 DA963119 DC360846 DQ891826 ABM82752 FN058159 HY170714 NM_001271918 NP_001258847 NM_001271919 NP_001258848 NM_001271920 NP_001258849 NM_001271921 NP_001258850 NM_001271922 NP_001258851 NM_014300 NP_055115 NR_073518
|
| Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
|
| Subcellular Location |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export
|
![Western Blot: SPC18 Overexpression Lysate (Adult Normal) [NBL1-15772] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPC18.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9439_SPC18%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15772-img0002.jpg)