ABCC6

Gene Symbol ABCC6
Entrez Gene 368
Alt Symbol ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7
Species Human
Gene Type protein-coding
Description ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Other Description ATP-binding cassette sub-family C member 6|anthracycline resistance-associated protein|multi-specific organic anion transporter E|multidrug resistance-associated protein 6
Swissprots A8Y988 A2RRN8 P78420 A8KIG6 E7ESW8 Q8TCY8 O95255 Q9UMZ7
Accessions AAC15785 EAW53950 EAW53951 EAW53952 O95255 AF076622 AAC79696 AF168791 AAD51293 AI074459 AK298295 BAG60553 AM711638 CAN84639 AM774324 CAO81806 AY078405 AAL83711 BC050733 AAH50733 BC131732 AAI31733 DC361874 XM_011522479 XP_011520781 XM_011522480 XP_011520782 XM_011522481 XP_011520783 XM_011522482 XP_011520784 XM_011546696 XP_011544998 XM_011546697 XP_011544999 XR_932836 XR_932837 XR_932838 XR_951901 XR_951902 XR_951903 NM_001079528 NP_001072996 NM_001171 NP_001162
Function Isoform 1: May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS). {ECO:0000269|PubMed:11880368}.
Subcellular Location Isoform 1: Basolateral cell membrane {ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}; Multi- pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12901863, ECO:0000269|PubMed:23625951}.
Tissue Specificity Expressed in kidney and liver. Very low expression in other tissues.
Top Pathways ABC transporters

MRP6 CRISPR/Cas9 KO Plasmid (h) - sc-402219 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 HDR Plasmid (h) - sc-402219-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 Double Nickase Plasmid (h) - sc-402219-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 Double Nickase Plasmid (h2) - sc-402219-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 CRISPR Activation Plasmid (h) - sc-402219-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 CRISPR Activation Plasmid (h2) - sc-402219-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 Lentiviral Activation Particles (h) - sc-402219-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 Lentiviral Activation Particles (h2) - sc-402219-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MRP6 siRNA (h) - sc-35967 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP6 shRNA Plasmid (h) - sc-35967-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MRP6 shRNA (h) Lentiviral Particles - sc-35967-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU072241 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU018191 from Sigma-Aldrich

Category siRNA

MISSION® 3′UTR Lenti GoClone™ - HUTR04207 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04207

ABCC6 siRNA (Human) - CRH0263 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC6 - MBS8220336 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human ABCC6 siRNA - orb260765 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ABCC6 shRNA Plasmid (Human) - CHH0263 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ABCC6 miRNA 3'UTR clone - MiUTR3H-05792 from Creative biogene

Species Reactivities Human

ABCC6 miRNA 3'UTR clone - MiUTR3H-05793 from Creative biogene

Species Reactivities Human
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