SGPL1

Gene Symbol	SGPL1
Entrez Gene	8879
Alt Symbol	S1PL, SPL
Species	Human
Gene Type	protein-coding
Description	sphingosine-1-phosphate lyase 1
Other Description	SP-lyase 1|SPL 1|hSPL|sphingosine-1-phosphate aldolase
Swissprots	Q7Z732 Q9ULG8 O95470 B2RBD4 Q9UN89
Accessions	CAM35395 EAW54414 O95470 AB033078 BAA86566 AF144638 AAD44755 AJ011304 CAA09590 AK023873 AK308610 AK314615 BAG37181 BC031338 BC041567 BC051238 BC052991 AAH52991 BC068061 BP314104 XM_005270263 XP_005270320 XM_006718053 XP_006718116 XM_011540316 XP_011538618 XM_011540317 XP_011538619 XM_011540318 XP_011538620 XM_011540319 XP_011538621 NM_003901 NP_003892
Function	Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. {ECO:0000269|PubMed:11018465, ECO:0000269|PubMed:14570870, ECO:0000269|PubMed:24809814}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Tissue Specificity	Found in liver and kidney. {ECO:0000269|PubMed:11018465}.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SGPL1 ORF clone(NM_003901.3) - CDCL186174 from Creative Biomart Species Human Accession NM_003901.3

human SGPL1 ORF clone - CDCH079578 from Creative Biomart Species Human Accession NM_003901

human SGPL1 ORF clone - CDCH079579 from Creative Biomart Species Human Accession NM_003901

human SGPL1 ORF clone - CDCH079580 from Creative Biomart Species Human Accession NM_003901

human SGPL1 ORF clone - CDCH079581 from Creative Biomart Species Human Accession NM_003901

Human SGPL1 Gene ORF cDNA clone in cloning vector - HG11395-M from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11395-ANG from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11395-NM from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11395-CF from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11395-CM from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11395-NY from Sino Biological Species Human

Human SGPL1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11395-M-N from Sino Biological Species Human Accession NM_003901.3

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11395-ACR from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11395-ANR from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid - HG11395-UT from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11395-CY from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11395-CH from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11395-ACG from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11395-NH from Sino Biological Species Human

Human SGPL1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11395-NF from Sino Biological Species Human

Human SGPL1 ORF clone(NM_003901.3) - CDCL186174 from Creative biogene Species Human

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