SGPL1

Gene Symbol SGPL1
Entrez Gene 8879
Alt Symbol S1PL, SPL
Species Human
Gene Type protein-coding
Description sphingosine-1-phosphate lyase 1
Other Description SP-lyase 1|SPL 1|hSPL|sphingosine-1-phosphate aldolase
Swissprots Q7Z732 Q9ULG8 O95470 B2RBD4 Q9UN89
Accessions CAM35395 EAW54414 O95470 AB033078 BAA86566 AF144638 AAD44755 AJ011304 CAA09590 AK023873 AK308610 AK314615 BAG37181 BC031338 BC041567 BC051238 BC052991 AAH52991 BC068061 BP314104 XM_005270263 XP_005270320 XM_006718053 XP_006718116 XM_011540316 XP_011538618 XM_011540317 XP_011538619 XM_011540318 XP_011538620 XM_011540319 XP_011538621 NM_003901 NP_003892
Function Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. {ECO:0000269|PubMed:11018465, ECO:0000269|PubMed:14570870, ECO:0000269|PubMed:24809814}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Tissue Specificity Found in liver and kidney. {ECO:0000269|PubMed:11018465}.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

SGPL1 293T Cell Transient Overexpression Lysate(Denatured) - H00008879-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SGPL1 overexpression lysate - LY418357 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SGPL1 Overexpression Lysate (Native) - NBP2-07936 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SGPL1 Overexpression Lysate (Adult Normal) [NBP2-07936] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SGPL1.

SGPL1 Overexpression Lysate (Denatured) - H00008879-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human SGPL1 Knockdown Stable Cell Line - CSC-DC014144 from Creative biogene

Category Cell Line
Species Human
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