Gene Symbol | HIST1H2BJ |
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Entrez Gene | 8970 |
Alt Symbol | H2B/r, H2BFR, H2BJ |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bj |
Other Description | H2B histone family, member R|histone 1, H2bj|histone H2B type 1-J|histone H2B.1|histone H2B.r |
Swissprots | P06899 B2R4J4 O60816 |
Accessions | AAN06693 CAA24950 EAX03080 EAX03081 EAX03082 P06899 AK311849 BAG34791 BC014312 NM_021058 NP_066402 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BJ CRISPR/Cas9 KO Plasmid (h) - sc-411231 from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ HDR Plasmid (h) - sc-411231-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ Double Nickase Plasmid (h) - sc-411231-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ Double Nickase Plasmid (h2) - sc-411231-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ CRISPR Activation Plasmid (h) - sc-411231-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ CRISPR Activation Plasmid (h2) - sc-411231-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ Lentiviral Activation Particles (h) - sc-411231-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ Lentiviral Activation Particles (h2) - sc-411231-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ siRNA (h) - sc-105480 from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ shRNA Plasmid (h) - sc-105480-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BJ shRNA (h) Lentiviral Particles - sc-105480-V from Santa Cruz Biotechnology
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HIST1H2BJ RNAi - H00008970-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10077 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10077 from Sigma-Aldrich
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HIST1H2BJ siRNA (Human) - CRH5920 from Cohesion Biosciences
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HIST1H2BJ - MBS8202976 from MyBioSource
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shRNA set against Human HIST1H2BJ (NM_021058.3) - SHH312625 from Creative biogene
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shRNA set against Human HIST1H2BJ(NM_021058.3) - SHH122509 from Creative biogene
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Human HIST1H2BJ siRNA - orb266422 from Biorbyt
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HIST1H2BJ shRNA Plasmid (Human) - CHH5920 from Cohesion Biosciences
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HIST1H2BJ miRNA 3'UTR clone - MiUTR1H-04538 from Creative biogene
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