| Gene Symbol |
HIST1H2BJ
|
| Entrez Gene |
8970
|
| Alt Symbol |
H2B/r, H2BFR, H2BJ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
histone cluster 1, H2bj
|
| Other Description |
H2B histone family, member R|histone 1, H2bj|histone H2B type 1-J|histone H2B.1|histone H2B.r
|
| Swissprots |
P06899 B2R4J4 O60816
|
| Accessions |
AAN06693 CAA24950 EAX03080 EAX03081 EAX03082 P06899 AK311849 BAG34791 BC014312 NM_021058 NP_066402
|
| Function |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
|
| Subcellular Location |
Nucleus. Chromosome.
|
| Top Pathways |
Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism
|