| Gene Symbol |
ECI2
|
| Entrez Gene |
10455
|
| Alt Symbol |
ACBD2, DRS-1, DRS1, HCA88, PECI, dJ1013A10.3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
enoyl-CoA delta isomerase 2
|
| Other Description |
D3,D2-enoyl-CoA isomerase|DBI-related protein 1|acyl-Coenzyme A binding domain containing 2|delta(3),delta(2)-enoyl-CoA isomerase|diazepam-binding inhibitor-related protein 1|dodecenoyl-CoA isomerase|enoyl-CoA delta isomerase 2, mitochondrial|hepatocellular carcinoma-associated antigen 88|peroxisomal 3,2-trans-enoyl-CoA isomerase|peroxisomal D3,D2-enoyl-CoA isomerase|renal carcinoma antigen NY-REN-1
|
| Swissprots |
Q9BUE9 Q7L124 O75521 Q5JYK7 Q5JYK5 Q9UN55 Q9NYH7 Q9H0T9 Q8N0X0 Q9NQH1
|
| Accessions |
CAF86353 EAW55158 EAW55159 EAW55160 EAW55161 EAW55162 EAW55163 EAW55164 O75521 AB209917 BAD93154 AF069301 AAC19317 AF153612 AAD34173 AF244138 AAF66247 AF257175 AAF68974 AK057175 AK075108 BAG52068 AK222617 BAD96337 AK223003 BAD96723 AK297049 BAG59575 AL136642 CAB66577 AU100345 AY297537 BC002668 AAH02668 BC008458 BC016781 AAH16781 BC017474 AAH17474 BC025287 BC033841 AAH33841 BC034702 AAH34702 BM671011 BQ653836 CR456768 CAG33049 EU832092 ACE87442 EU832093 ACE87443 EU832094 ACE87444 EU832184 ACE86754 EU832185 ACE86755 EU832186 ACE86756 XM_006714957 XP_006715020 NM_001166010 NP_001159482 NM_006117 NP_006108 NM_206836 NP_996667 NR_028588
|
| Function |
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Isoform 1: Mitochondrion {ECO:0000250}.
|
| Tissue Specificity |
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells. {ECO:0000269|PubMed:15217832}.
|
| Top Pathways |
Peroxisome, Fatty acid degradation
|