ECI2

Gene Symbol ECI2
Entrez Gene 10455
Alt Symbol ACBD2, DRS-1, DRS1, HCA88, PECI, dJ1013A10.3
Species Human
Gene Type protein-coding
Description enoyl-CoA delta isomerase 2
Other Description D3,D2-enoyl-CoA isomerase|DBI-related protein 1|acyl-Coenzyme A binding domain containing 2|delta(3),delta(2)-enoyl-CoA isomerase|diazepam-binding inhibitor-related protein 1|dodecenoyl-CoA isomerase|enoyl-CoA delta isomerase 2, mitochondrial|hepatocellular carcinoma-associated antigen 88|peroxisomal 3,2-trans-enoyl-CoA isomerase|peroxisomal D3,D2-enoyl-CoA isomerase|renal carcinoma antigen NY-REN-1
Swissprots Q9BUE9 Q7L124 O75521 Q5JYK7 Q5JYK5 Q9UN55 Q9NYH7 Q9H0T9 Q8N0X0 Q9NQH1
Accessions CAF86353 EAW55158 EAW55159 EAW55160 EAW55161 EAW55162 EAW55163 EAW55164 O75521 AB209917 BAD93154 AF069301 AAC19317 AF153612 AAD34173 AF244138 AAF66247 AF257175 AAF68974 AK057175 AK075108 BAG52068 AK222617 BAD96337 AK223003 BAD96723 AK297049 BAG59575 AL136642 CAB66577 AU100345 AY297537 BC002668 AAH02668 BC008458 BC016781 AAH16781 BC017474 AAH17474 BC025287 BC033841 AAH33841 BC034702 AAH34702 BM671011 BQ653836 CR456768 CAG33049 EU832092 ACE87442 EU832093 ACE87443 EU832094 ACE87444 EU832184 ACE86754 EU832185 ACE86755 EU832186 ACE86756 XM_006714957 XP_006715020 NM_001166010 NP_001159482 NM_006117 NP_006108 NM_206836 NP_996667 NR_028588
Function Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity). {ECO:0000250}.
Subcellular Location Isoform 1: Mitochondrion {ECO:0000250}.
Tissue Specificity Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells. {ECO:0000269|PubMed:15217832}.
Top Pathways Peroxisome, Fatty acid degradation

PECI (32) - sc-136374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PECI (32): sc-136374. Western blot analysis of PECI Isoform 2 expression in rat liver tissue extract.

PECI (P-19) - sc-82692 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PECI (P-19): sc-82692. Western blot analysis of PECI expression in 293T whole cell lysate.

Anti-PECI antibody - ab151413 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PECI antibody (ab151413) at 1/5000 dilution + Raji whole cell lysate at 30 µg

Anti-PECI antibody - ab70512 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PECI antibody (ab70512) at 1/500 dilution + human liver tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PECI antibody - ab83029 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PECI antibody (ab83029) at 1 µg/ml (5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PECI antibody - ab90655 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-PECI antibody (ab90655) at 1/500 dilution + Jurkat cell lysate

Anti-PECI antibody - ab137966 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PECI antibody (ab137966) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-PECI antibody - ab93176 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PECI antibody (ab93176) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-PECI antibody [1H4] - ab119383 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1H4
All lanes : Anti-PECI antibody [1H4] (ab119383) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected withpCMV6-ENTRY PECI cDNALysates/proteins at 5 µg per lane.

Anti-ECI2 / PECI Antibody (aa73-122) IHC-plus™ - LS-B8576 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ECI2 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8576 dilution 5 ug/ml.

Anti-ECI2 / PECI Antibody (clone 1C8) - LS-C337624 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C8
IHC of paraffin-embedded Human liver tissue using anti-PECI mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-ECI2 / PECI Antibody (Glu105) - LS-C192120 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, AP) - LS-C280711 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, APC) - LS-C280712 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, Biotin) - LS-C280713 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, FITC) - LS-C280714 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, Azide-free, HRP) - LS-C280715 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (aa216-265) - LS-C81278 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ECI2 / PECI Antibody (C-Terminus) - LS-C328176 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (C-Terminus, PE) - LS-C280716 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (aa56-105) - LS-C200478 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from COLO205 cells using PECI antibody.

Anti-ECI2 / PECI Antibody (clone 1H4) - LS-C173700 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PECI (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PECI.

Anti-ECI2 / PECI Antibody (clone 2H10) - LS-C173811 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PECI (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PECI.

Anti-ECI2 / PECI Antibody - LS-C137229 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ECI2 / PECI Antibody (aa331-358) - LS-C163512 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human skeletal muscle reacted with PECI Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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