CD74

Gene Symbol	CD74
Entrez Gene	972
Alt Symbol	DHLAG, HLADG, II, Ia-GAMMA
Species	Human
Gene Type	protein-coding
Description	CD74 molecule, major histocompatibility complex, class II invariant chain
Other Description	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)|HLA class II histocompatibility antigen gamma chain|HLA-DR antigens-associated invariant chain|HLA-DR-gamma|Ia-associated invariant chain|MHC HLA-DR gamma chain|gamma chain of class II antigens|p33
Swissprots	D3DQG3 A8K7R1 Q8SNA0 B4DNE8 Q8WLP6 Q5U0J8 D3DQG4 Q14597 Q29832 P04233
Accessions	AAA36033 CAA27046 CAA27047 EAW61727 EAW61728 EAW61729 EAW61730 EAW61731 P04233 AK292076 BAF84765 AK297889 BAG60210 AK300669 BAG62354 AK308929 BC018726 AAH18726 BC024272 AAH24272 BF796148 BT019505 AAV38312 DC354760 DQ892005 ABM82931 DQ895194 ABM86120 K01144 AAA36304 M28588 AAA58655 M28589 AAO49820 M28590 AAA35996 X00497 CAA25192 NM_001025158 NP_001020329 NM_001025159 NP_001020330 NM_004355 NP_004346
Function	Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Note=Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.
Top Pathways	Tuberculosis, Herpes simplex infection, Antigen processing and presentation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CD74 / CLIP ELISA Kit (Sandwich ELISA) - LS-F11627 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.625 ng/ml Range 0.625-40 ng/ml

HLA class II histocompatibility antigen gamma chain (CD74), Human, ELISA Kit - CSB-EL004956HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.22 ng/ml Range 0.9 ng/ml-60 ng/ml

HLA class II histocompatibility antigen gamma chain, CD74, Human, ELISA Kit - E13627h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.625-40 ng/mL

CD74 (Human) IP-WB Antibody Pair - H00000972-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

CD74 molecule, major histocompatibility complex, class II invariant chain, ELISA Kit - MBS920059 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human CD74 is typically less than 0.225 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.9 ng/ml -60 ng/ml.

Cluster of Differentiation 74, ELISA Kit - MBS750358 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS753696 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS745538 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS752501 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS751738 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS745351 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Cluster of Differentiation 74, ELISA Kit - MBS746889 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Cluster of Differentiation 74, ELISA Kit - MBS749992 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS746423 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS754118 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS751821 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cluster of Differentiation 74, ELISA Kit - MBS751829 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Human HLA class II histocompatibility antigen gamma chain(CD74) ELISA kit - CSB-EL004956HU from Cusabio Category ELISA Kit Sensitivity 0.225 ng/ml Range 0.9 ng/ml-60 ng/ml

Mouse CD74 / CLIP ELISA Kit (Custom ELISA) - LS-F17026 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.625-40 ng/ml

Rat CD74 / CLIP ELISA Kit (Sandwich ELISA) - LS-F17027 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 ng/ml Range 0.625-40 ng/ml

Human HLA class II histocompatibility antigen gamma chain ELISA Kit - abx250817 from Abbexa Category ELISA Kit Range 0.625 ng/ml - 40 ng/ml

Custom Human CD74 ELISA - ELH-CD74 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human CD74(HLA class Ⅱ histocompatibility antigen gamma chain) ELISA Kit - E-EL-H2530 from Elabscience Category ELISA Kit Sensitivity 0.38 ng/mL Range 0.63—40 ng/mL

Human CD74 ELISA Kit - orb319912 from Biorbyt Category ELISA Kit Prices $884.00, $1,513.00, $3,239.00 Sizes 96 assays, 192 assays, 480 assays

Human CD74 ELISA - RAB1351 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Search more