ATP2B4

Gene Symbol	ATP2B4
Entrez Gene	493
Alt Symbol	ATP2B2, MXRA1, PMCA4, PMCA4b, PMCA4x
Species	Human
Gene Type	protein-coding
Description	ATPase, Ca++ transporting, plasma membrane 4
Other Description	matrix-remodeling-associated protein 1|plasma membrane calcium-transporting ATPase 4|sarcolemmal calcium pump
Swissprots	Q16817 Q13455 B1APW5 B1APW6 Q13450 Q7Z3S1 Q13452 P23634
Accessions	EAW91483 EAW91484 EAW91485 EAW91486 EAW91487 P23634 AK026443 AK292458 BAF85147 AK307104 AL601702 AL706212 AM393326 CAL38204 AM393354 CAL38232 AW888226 BC062445 BC140774 AAI40775 BC150293 AAI50294 BF740130 BF985985 BX537444 CAD97686 BX537745 BX647701 CR749393 CAH18241 CR936708 DN997129 DQ201780 ABG24244 DQ201781 ABG24245 M25874 AAA50819 M83363 AAA36455 U42026 AAB17577 U42061 AAB17578 U42062 AAB17579 U42378 AAB17580 NM_001001396 NP_001001396 NM_001684 NP_001675
Function	This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Isoform XB is the most abundant isoform and is expressed ubiquitously. Isoforms containing segment Z have only been detected in heart, while isoforms containing segment a have been found in heart, stomach and brain cortex.
Top Pathways	Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Calcium Pump PMCA4 ATPase protein fragment - ab114628 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

ATP2B4 / PMCA4 Antibody Blocking Peptide - LS-E3356 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PMCA4 Protein - H00000493-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ATP2B4-Antibody-C-term-Blocking-Peptide - BP14531b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ATP2B4 Blocking Peptide - 33R-2841 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATP2B4 / PMCA4 - H00000493-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP2B4 / PMCA4 - H00000493-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP2B4 fusion protein - Ag23048 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PET30a Species Human

Recombinant Human ATP2B4 - ATP2B4-27795TH from Creative Biomart Category Protein Source Wheat germ

ATP2B4 / PMCA4 (transcript variant 2) - TP313835 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Plasma membrane calcium-transporting ATPase 4 (ATP2B4), partial, Recombinant Protein - MBS966630 from MyBioSource Category Protein Prices $1,390.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PMCA4 Recombinant Protein Antigen - NBP2-31984PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ATP2B4 Peptide, Human - M34GP01147H from Creative Peptides Category Peptide Source Synthetic. Species Human

PDZ domain scaffold protein anti-Human hPMCA4b - SPD-L151 from Creative Biolabs Category Protein Source E. coli Species Human

ATP2B4 fusion protein - Ag22843 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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