Gene Symbol | RNASE2 |
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Entrez Gene | 6036 |
Alt Symbol | EDN, RAF3, RNS2 |
Species | Human |
Gene Type | protein-coding |
Description | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
Other Description | RNase 2|RNase UpI-2|eosinophil-derived neurotoxin|non-secretory ribonuclease|ribonuclease 2|ribonuclease A F3|ribonuclease US |
Swissprots | Q9H2B7 P10153 Q52M39 Q9UCG7 |
Accessions | AAG31577 AAG31578 AAG31579 AAG31580 AAG31581 AAG31582 AAG31583 AAG31584 AAG31585 CAA34546 CAA39459 CAC27640 CDG31919 EAW66435 P10153 BC093678 AAH93678 BC093680 AAH93680 BC096059 AAH96059 M24157 AAA52337 M28129 AAA50284 M30510 AAC82505 X55988 CAA39460 NM_002934 NP_002925 |
Function | This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. {ECO:0000269|PubMed:12578357, ECO:0000269|PubMed:3458170}. |
Subcellular Location | Lysosome {ECO:0000305}. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule. |
Tissue Specificity | Liver, lung, spleen, leukocytes and body fluids. |
RNase 2 (T-13) - sc-165368 from Santa Cruz Biotechnology
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RNase 2 (C-13) - sc-165366 from Santa Cruz Biotechnology
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Anti-Eosinophil derived neurotoxin antibody - ab103428 from Abcam
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Anti-Eosinophil derived neurotoxin antibody - ab59750 from Abcam
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Anti-RNASE2 / EDN Antibody (clone 3H8) - LS-C84102 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody - LS-C122391 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa1-161) - LS-C131909 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, AP) - LS-C268333 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, APC) - LS-C285059 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, Biotin) - LS-C285061 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, FITC) - LS-C285062 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, Azide-free, HRP) - LS-C285063 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152, PE) - LS-C285064 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody - LS-C285598 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (Biotin) - LS-C316886 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (HRP) - LS-C316888 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (FITC) - LS-C316887 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152) - LS-C324703 from LifeSpan Bioscience
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Anti-RNASE2 / EDN Antibody (aa124-152) - LS-C158859 from LifeSpan Bioscience
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Eosinophil derived neurotoxin Antibody - NBP1-91872 from Novus Biologicals
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Eosinophil derived neurotoxin Antibody - H00006036-B01P from Novus Biologicals
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Eosinophil derived neurotoxin Antibody - H00006036-A01 from Novus Biologicals
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Anti-RNASE2 antibody produced in rabbit - HPA044983 from Sigma-Aldrich
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Anti-RNASE2 antibody produced in mouse - SAB1406393 from Sigma-Aldrich
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Anti-RNASE2 antibody produced in rabbit - SAB1401337 from Sigma-Aldrich
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