Gene Symbol | ARL6IP1 |
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Entrez Gene | 23204 |
Alt Symbol | AIP1, ARL6IP, ARMER, SPG61 |
Species | Human |
Gene Type | protein-coding |
Description | ADP-ribosylation factor-like 6 interacting protein 1 |
Other Description | ADP-ribosylation factor-like protein 6-interacting protein 1|ARL-6-interacting protein 1|aip-1|apoptotic regulator in the membrane of the endoplasmic reticulum |
Swissprots | B7Z6S5 B7Z791 Q15041 F5GXP4 |
Accessions | EAW50257 EAW50258 Q15041 AK291137 BAF83826 AK300825 BAH13355 AK300869 BAH13361 AK301636 BAH13527 AK307315 AK308092 AK308744 BC010281 AAH10281 BX648446 D31885 BAA06683 HQ448378 ADQ32858 NM_015161 NP_055976 |
Function | May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. |
Subcellular Location | Endomembrane system {ECO:0000269|PubMed:10995579}; Multi-pass membrane protein {ECO:0000269|PubMed:10995579}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24076029}; Multi-pass membrane protein {ECO:0000269|PubMed:24076029}. Note=Predominantly localized to intracytoplasmic membranes. |
Tissue Specificity | Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart. {ECO:0000269|PubMed:10995579}. |
ARMER CRISPR/Cas9 KO Plasmid (h) - sc-409837 from Santa Cruz Biotechnology
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ARMER HDR Plasmid (h) - sc-409837-HDR from Santa Cruz Biotechnology
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ARMER Double Nickase Plasmid (h) - sc-409837-NIC from Santa Cruz Biotechnology
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ARMER Double Nickase Plasmid (h2) - sc-409837-NIC-2 from Santa Cruz Biotechnology
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ARMER CRISPR Activation Plasmid (h) - sc-409837-ACT from Santa Cruz Biotechnology
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ARMER CRISPR Activation Plasmid (h2) - sc-409837-ACT-2 from Santa Cruz Biotechnology
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ARMER Lentiviral Activation Particles (h) - sc-409837-LAC from Santa Cruz Biotechnology
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ARMER Lentiviral Activation Particles (h2) - sc-409837-LAC-2 from Santa Cruz Biotechnology
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ARMER siRNA (h) - sc-61994 from Santa Cruz Biotechnology
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ARMER shRNA Plasmid (h) - sc-61994-SH from Santa Cruz Biotechnology
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ARMER shRNA (h) Lentiviral Particles - sc-61994-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU145221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3497 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3497 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10015 from Sigma-Aldrich
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ARL6IP1 siRNA (Human) - CRH8083 from Cohesion Biosciences
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ARMER RNAi - H00023204-R01 from Novus Biologicals
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ARL6IP1 - MBS8224677 from MyBioSource
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shRNA set against Human ARL6IP1 (NM_015161.1) - SHH240286 from Creative biogene
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shRNA set against Human ARL6IP1(NM_015161.1) - SHG072919 from Creative biogene
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Human ARL6IP1 siRNA - orb268585 from Biorbyt
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ARL6IP1 shRNA Plasmid (Human) - CHH8083 from Cohesion Biosciences
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ARL6IP1 miRNA 3'UTR clone - MiUTR1H-00572 from Creative biogene
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