| Gene Symbol |
ARL6IP1
|
| Entrez Gene |
23204
|
| Alt Symbol |
AIP1, ARL6IP, ARMER, SPG61
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ADP-ribosylation factor-like 6 interacting protein 1
|
| Other Description |
ADP-ribosylation factor-like protein 6-interacting protein 1|ARL-6-interacting protein 1|aip-1|apoptotic regulator in the membrane of the endoplasmic reticulum
|
| Swissprots |
B7Z6S5 B7Z791 Q15041 F5GXP4
|
| Accessions |
EAW50257 EAW50258 Q15041 AK291137 BAF83826 AK300825 BAH13355 AK300869 BAH13361 AK301636 BAH13527 AK307315 AK308092 AK308744 BC010281 AAH10281 BX648446 D31885 BAA06683 HQ448378 ADQ32858 NM_015161 NP_055976
|
| Function |
May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
|
| Subcellular Location |
Endomembrane system {ECO:0000269|PubMed:10995579}; Multi-pass membrane protein {ECO:0000269|PubMed:10995579}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24076029}; Multi-pass membrane protein {ECO:0000269|PubMed:24076029}. Note=Predominantly localized to intracytoplasmic membranes.
|
| Tissue Specificity |
Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart. {ECO:0000269|PubMed:10995579}.
|
![Western Blot: ARMER Overexpression Lysate (Adult Normal) [NBL1-07700] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARMER.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6980_ARMER%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07700-img0002.jpg)