Gene Symbol | RASGEF1A |
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Entrez Gene | 221002 |
Alt Symbol | CG4853 |
Species | Human |
Gene Type | protein-coding |
Description | RasGEF domain family, member 1A |
Other Description | CG4853 gene product|ras-GEF domain-containing family member 1A |
Swissprots | Q8TBF1 Q8N9B8 |
Accessions | CAS02256 EAW86590 EAW86591 Q8N9B8 AI862588 AK095136 BAC04491 AK127432 BAG54503 BC022548 AAH22548 HY118234 XM_005271809 XP_005271866 XM_011539499 XP_011537801 XM_011539500 XP_011537802 NM_001282862 NP_001269791 NM_145313 NP_660356 |
Function | Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration. {ECO:0000269|PubMed:17121879, ECO:0000269|PubMed:19645719}. |
Tissue Specificity | Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies. {ECO:0000269|PubMed:17121879}. |
RASGEF1A CRISPR/Cas9 KO Plasmid (h) - sc-415115 from Santa Cruz Biotechnology
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RASGEF1A HDR Plasmid (h) - sc-415115-HDR from Santa Cruz Biotechnology
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RASGEF1A Double Nickase Plasmid (h) - sc-415115-NIC from Santa Cruz Biotechnology
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RASGEF1A Double Nickase Plasmid (h2) - sc-415115-NIC-2 from Santa Cruz Biotechnology
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RASGEF1A CRISPR Activation Plasmid (h) - sc-415115-ACT from Santa Cruz Biotechnology
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RASGEF1A CRISPR Activation Plasmid (h2) - sc-415115-ACT-2 from Santa Cruz Biotechnology
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RASGEF1A Lentiviral Activation Particles (h) - sc-415115-LAC from Santa Cruz Biotechnology
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RASGEF1A Lentiviral Activation Particles (h2) - sc-415115-LAC-2 from Santa Cruz Biotechnology
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RASGEF1A siRNA (h) - sc-90732 from Santa Cruz Biotechnology
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RASGEF1A shRNA Plasmid (h) - sc-90732-SH from Santa Cruz Biotechnology
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RASGEF1A shRNA (h) Lentiviral Particles - sc-90732-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU102121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17979 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17979 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10000 from Sigma-Aldrich
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RASGEF1A siRNA (Human) - CRJ6480 from Cohesion Biosciences
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RASGEF1A - MBS8226347 from MyBioSource
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shRNA set against Human RASGEF1A (NM_145313.2) - SHH389968 from Creative biogene
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Human RASGEF1A siRNA - orb276981 from Biorbyt
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RASGEF1A shRNA Plasmid (Human) - CHJ6480 from Cohesion Biosciences
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RASGEF1A miRNA 3'UTR clone - MiUTR1H-08642 from Creative biogene
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