| Gene Symbol |
RASGEF1A
|
| Entrez Gene |
221002
|
| Alt Symbol |
CG4853
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RasGEF domain family, member 1A
|
| Other Description |
CG4853 gene product|ras-GEF domain-containing family member 1A
|
| Swissprots |
Q8TBF1 Q8N9B8
|
| Accessions |
CAS02256 EAW86590 EAW86591 Q8N9B8 AI862588 AK095136 BAC04491 AK127432 BAG54503 BC022548 AAH22548 HY118234 XM_005271809 XP_005271866 XM_011539499 XP_011537801 XM_011539500 XP_011537802 NM_001282862 NP_001269791 NM_145313 NP_660356
|
| Function |
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration. {ECO:0000269|PubMed:17121879, ECO:0000269|PubMed:19645719}.
|
| Tissue Specificity |
Detected in brain and spinal cord. Highly expressed in a number of intrahepatic cholangiocarcinoma tissue biopsies. {ECO:0000269|PubMed:17121879}.
|