RFC1

Gene Symbol RFC1
Entrez Gene 5981
Alt Symbol A1, MHCBFB, PO-GA, RECC1, RFC, RFC140
Species Human
Gene Type protein-coding
Description replication factor C (activator 1) 1, 145kDa
Other Description A1 140 kDa subunit|DNA-binding protein PO-GA|MHC binding factor, beta|RF-C 140 kDa subunit|activator 1 140 kDa subunit|activator 1 large subunit|activator 1 subunit 1|replication factor C 140 kDa subunit|replication factor C large subunit|replication factor C subunit 1|replication factor C1
Swissprots Q6PKU0 A8K6E7 Q86V46 Q5XKF5 P35251 Q86V41
Accessions AAS94325 EAW92922 EAW92923 EAW92924 P35251 AF040250 AAB99788 AJ564999 CAD92367 AK291612 BAF84301 BC010387 BC035297 AAH35297 BC051751 AAH51751 BC051786 AAH51786 DA336360 EU447003 ABZ92532 L23320 AAA16121 L24783 X69821 CAA49475 XM_011513730 XP_011512032 XM_011513731 XP_011512033 NM_001204747 NP_001191676 NM_002913 NP_002904
Function The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. {ECO:0000269|PubMed:8999859}.
Subcellular Location Nucleus.
Tissue Specificity Wide tissue distribution. Undetectable in placental tissue.
Top Pathways DNA replication, Mismatch repair, Nucleotide excision repair

RFC1 CRISPR/Cas9 KO Plasmid (h) - sc-402122 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 HDR Plasmid (h) - sc-402122-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 Double Nickase Plasmid (h) - sc-402122-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 Double Nickase Plasmid (h2) - sc-402122-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 CRISPR Activation Plasmid (h) - sc-402122-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 CRISPR Activation Plasmid (h2) - sc-402122-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 Lentiviral Activation Particles (h) - sc-402122-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 Lentiviral Activation Particles (h2) - sc-402122-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RFC1 siRNA (h) - sc-37631 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RFC1 shRNA Plasmid (h) - sc-37631-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RFC1 shRNA (h) Lentiviral Particles - sc-37631-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU049251 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18164 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18164 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08859 from Sigma-Aldrich

Category miRNA

RFC1 siRNA (Human) - CRH4049 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RFC1 RNAi - H00005981-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

RFC1 - MBS8228544 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RFC1 (NM_002913.4) - SHH392180 from Creative biogene

Category siRNA
Species Reactivities Human

RFC1 shRNA Plasmid (Human) - CHH4049 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RFC1 miRNA 3'UTR clone - MiUTR3H-00037 from Creative biogene

Species Reactivities Human
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