RFC1

Gene Symbol	RFC1
Entrez Gene	5981
Alt Symbol	A1, MHCBFB, PO-GA, RECC1, RFC, RFC140
Species	Human
Gene Type	protein-coding
Description	replication factor C (activator 1) 1, 145kDa
Other Description	A1 140 kDa subunit|DNA-binding protein PO-GA|MHC binding factor, beta|RF-C 140 kDa subunit|activator 1 140 kDa subunit|activator 1 large subunit|activator 1 subunit 1|replication factor C 140 kDa subunit|replication factor C large subunit|replication factor C subunit 1|replication factor C1
Swissprots	Q6PKU0 A8K6E7 Q86V46 Q5XKF5 P35251 Q86V41
Accessions	AAS94325 EAW92922 EAW92923 EAW92924 P35251 AF040250 AAB99788 AJ564999 CAD92367 AK291612 BAF84301 BC010387 BC035297 AAH35297 BC051751 AAH51751 BC051786 AAH51786 DA336360 EU447003 ABZ92532 L23320 AAA16121 L24783 X69821 CAA49475 XM_011513730 XP_011512032 XM_011513731 XP_011512033 NM_001204747 NP_001191676 NM_002913 NP_002904
Function	The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. {ECO:0000269|PubMed:8999859}.
Subcellular Location	Nucleus.
Tissue Specificity	Wide tissue distribution. Undetectable in placental tissue.
Top Pathways	DNA replication, Mismatch repair, Nucleotide excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RFC1 protein fragment - ab127089 from Abcam Category Protein Source E. coli Species Human

RFC1-Antibody-N-term-Blocking-Peptide - BP19110a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

RFC1 / RFC140 - H00005981-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

RFC1 / RFC140 - H00005981-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

RFC1 fusion protein - ag13585 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Replication factor C subunit 1(RFC1) ,partial - CSB-YP019588HU CSB-EP019588HU CSB-BP019588HU CSB-MP019588HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

RFC1 Blocking Peptide - CBP5431 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

RFC1 Recombinant Protein Antigen - NBP2-54960PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1071360 from MyBioSource Category Protein Prices $1,250.00, $1,250.00, $1,470.00, $1,470.00, $2,040.00, $2,040.00, $2,500.00, $2,500.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Pyrococcus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1322510 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,925.00, $1,925.00, $2,390.00, $2,390.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1117455 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,530.00, $2,530.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1264406 from MyBioSource Category Protein Prices $1,260.00, $1,260.00, $1,475.00, $1,475.00, $2,050.00, $2,050.00, $2,515.00, $2,515.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Methanococcus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1355302 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,075.00, $2,075.00, $2,540.00, $2,540.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1142571 from MyBioSource Category Protein Prices $1,280.00, $1,280.00, $1,495.00, $1,495.00, $2,095.00, $2,095.00, $2,560.00, $2,560.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Methanococcus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1303870 from MyBioSource Category Protein Prices $1,285.00, $1,285.00, $1,500.00, $1,500.00, $2,105.00, $2,105.00, $2,570.00, $2,570.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1196354 from MyBioSource Category Protein Prices $1,180.00, $1,180.00, $1,400.00, $1,400.00, $1,890.00, $1,890.00, $2,355.00, $2,355.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Sulfolobus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1428295 from MyBioSource Category Protein Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,930.00, $1,930.00, $2,395.00, $2,395.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Pyrobaculum

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1099607 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,480.00, $1,480.00, $2,065.00, $2,065.00, $2,530.00, $2,530.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Methanothermobacter

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1349721 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,480.00, $1,480.00, $2,065.00, $2,065.00, $2,530.00, $2,530.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1185883 from MyBioSource Category Protein Prices $1,265.00, $1,265.00, $1,485.00, $1,485.00, $2,070.00, $2,070.00, $2,535.00, $2,535.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Methanococcus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1147742 from MyBioSource Category Protein Prices $1,185.00, $1,185.00, $1,405.00, $1,405.00, $1,910.00, $1,910.00, $2,375.00, $2,375.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1322593 from MyBioSource Category Protein Prices $1,260.00, $1,260.00, $1,480.00, $1,480.00, $2,060.00, $2,060.00, $2,525.00, $2,525.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Pyrococcus

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1037158 from MyBioSource Category Protein Prices $1,205.00, $1,205.00, $1,425.00, $1,425.00, $1,950.00, $1,950.00, $2,415.00, $2,415.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1095783 from MyBioSource Category Protein Prices $1,260.00, $1,260.00, $1,480.00, $1,480.00, $2,055.00, $2,055.00, $2,520.00, $2,520.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Replication factor C large subunit (rfcL), Recombinant Protein - MBS1425771 from MyBioSource Category Protein Prices $1,270.00, $1,270.00, $1,490.00, $1,490.00, $2,080.00, $2,080.00, $2,545.00, $2,545.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Methanococcus

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