ATP7A

Gene Symbol	ATP7A
Entrez Gene	538
Alt Symbol	DSMAX, MK, MNK, SMAX3
Species	Human
Gene Type	protein-coding
Description	ATPase, Cu++ transporting, alpha polypeptide
Other Description	Cu++-transporting P-type ATPase|Menkes disease-associated protein|copper pump 1|copper-transporting ATPase 1
Swissprots	O00227 Q9BYY8 B1AT72 O00745 Q04656
Accessions	AAA96010 AAG47452 CAB08160 CAB08162 CAB94714 CBL93959 EAW98605 EAW98606 Q04656 AB117973 BAC82353 AB208828 BAD92065 AK096667 AK299449 BAG61422 BC156437 AAI56438 BP364137 BU753163 BX503903 CD299174 DB164588 L06133 AAA35580 L06476 AAA16974 NM_000052 NP_000043 NM_001282224 NP_001269153 NR_104109
Function	May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
Subcellular Location	Isoform 5: Endoplasmic reticulum.
Tissue Specificity	Found in most tissues except liver. Isoform 3 is widely expressed including in liver cell lines. Isoform 1 is expressed in fibroblasts, choriocarcinoma, colon carcinoma and neuroblastoma cell lines. Isoform 2 is expressed in fibroblasts, colon carcinoma and neuroblastoma cell lines.
Top Pathways	Mineral absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ATP7A protein fragment - ab114343 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

MNK / ATP7A Blocking Peptide - LS-E11952 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MNK / ATP7A Antibody Blocking Peptide - LS-E11953 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MNK / ATP7A Antibody Blocking Peptide - LS-E26696 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ATP7A Protein - H00000538-Q01 from Novus Biologicals Category Protein Prices $319.00, $369.00, $529.00 Sizes 2 µg, 10 µg, 25 µg Source Wheat Germ Species Human

ATP7A blocking peptide - GTX88764-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

ATP7A Blocking Peptide - 33R-8820 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATP7A Blocking Peptide - 33R-6149 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ATP7A Peptide - AC21-1536-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ATP7A - H00000538-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ATP7A - H00000538-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ATP7A Peptide - 46-816P from ProSci Category Peptide

Recombinant Human ATP7A - ATP7A-27417TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Menkes Protein, Domain 1 - ATP7A-454H from Creative Biomart Category Protein Source Escherichia Coli .

Recombinant Human Menkes Protein, Domain 3 - ATP7A-456H from Creative Biomart Category Protein Source Escherichia Coli .

Recombinant Human ATPase, Cu++ Transporting, Alpha Polypeptide - ATP7A-459H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human ATPase, Cu++ Transporting, Alpha Polypeptide, His-tagged - ATP7A-460H from Creative Biomart Category Protein Source E.Coli.

Recombinant Human ATP7A, Domain 2 - ATP7A-455H from Creative Biomart Category Protein Source Escherichia Coli .

Recombinant Human ATP7A, Domain 5 - ATP7A-458H from Creative Biomart Category Protein Source Escherichia Coli.

ATP7A (H640) Peptide - BS3695P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

ATP7A Protein - abx163224 from Abbexa Category Protein Species Human

ATP7A, Peptide - MBS426572 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

ATP7A Blocking Peptide - abx061716 from Abbexa Category Peptide

ATP7A Recombinant Protein Antigen - NBP1-82631PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ATP7A Peptide, Human - M34GP01196H from Creative Peptides Category Peptide Source Synthetic. Species Human

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