Gene Symbol | KRT14 |
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Entrez Gene | 3861 |
Alt Symbol | CK14, EBS3, EBS4, K14, NFJ |
Species | Human |
Gene Type | protein-coding |
Description | keratin 14, type I |
Other Description | CK-14|cytokeratin 14|cytokeratin-14|keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)|keratin, type I cytoskeletal 14|keratin-14 |
Swissprots | Q14715 Q9BUE3 P02533 Q9UBN2 Q9UBN3 Q9UCY4 Q53XY3 |
Accessions | AAB59562 AAF04034 AAF04035 AAF04036 AAF04037 AAF04038 AAF04039 EAW60745 EAW60746 EAW60747 EAW60748 P02533 AK309280 BC002690 AAH02690 BC019097 AAH19097 BC042437 AAH42437 BC094830 AAH94830 BT007186 AAP35850 DB018715 DQ890733 ABM81659 DQ892997 ABM83923 DQ893905 ABM84831 M28646 AAA96689 NM_000526 NP_000517 |
Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. {ECO:0000269|PubMed:11724817}. |
Subcellular Location | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern. |
Tissue Specificity | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. {ECO:0000269|PubMed:9457912}. |
Human Cytokeratin 14 full length protein - ab73637 from Abcam
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KRT14 / CK14 / Cytokeratin 14 Antibody Blocking Peptide - LS-E10595 from LifeSpan Bioscience
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KRT14 / CK14 / Cytokeratin 14 Antibody Blocking Peptide - LS-E8407 from LifeSpan Bioscience
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Cytokeratin 14 Recombinant Protein - H00003861-P01 from Novus Biologicals
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Recombinant Human Cytokeratin 14 Protein - NBP1-72467 from Novus Biologicals
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KRT14-Antibody-Center-Blocking-Peptide - BP6713c from Abgent, a WuXi AppTec company
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KRT14 Protein (OPPA01262) - OPPA01262 from Aviva Systems Biology
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Human KRT14 protein - orb245902 from Biorbyt
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Human KRT14 protein (His Tag) - orb168709 from Biorbyt
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Human KRT14 protein - orb244331 from Biorbyt
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Human KRT14 protein - orb81182 from Biorbyt
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KRT14 peptide - orb217525 from Biorbyt
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Cytokeratin 14 protein - 30R-AC071 from Fitzgerald
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Keratin K14 protein - 30R-2120 from Fitzgerald
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Keratin K14 protein - 30R-2140 from Fitzgerald
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KRT14 Blocking Peptide - 33R-1854 from Fitzgerald
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KRT14 protein (His tag) - 80R-1981 from Fitzgerald
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Cytokeratin 14 Blocking Peptide - abx062856 from Abbexa
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Cytokeratin 14 - AR09363PU-N from Acris Antibodies
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Cytokeratin 14 - AR09363PU-S from Acris Antibodies
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Cytokeratin 14 (1-472, His-tag) - AR50050PU-N from Acris Antibodies
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Cytokeratin 14 (1-472, His-tag) - AR50050PU-S from Acris Antibodies
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Cytokeratin 14 - H00003861-P01-10 from Acris Antibodies
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Cytokeratin 14 - H00003861-P01-25 from Acris Antibodies
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Cytokeratin 14, Human Recombinant - 228-10997-1 from RayBiotech
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