MADCAM1

Gene Symbol	MADCAM1
Entrez Gene	8174
Alt Symbol	MACAM1
Species	Human
Gene Type	protein-coding
Description	mucosal vascular addressin cell adhesion molecule 1
Other Description	MAdCAM-1|hMAdCAM-1|mucosal addressin cell adhesion molecule 1|mucosal addressin cell adhesion molecule-1
Swissprots	Q5UGI7 A5PKV4 O60222 O75867 B2RPL9 Q13477
Accessions	AAC51354 AAC62844 EAW61194 EAW61195 Q13477 AK092211 AY732484 AAV33123 AY819760 AAV68345 BC136408 AAI36409 BC137506 AAI37507 BC137507 AAI37508 BC142629 AAI42630 BC144065 AAI44066 DB323303 DQ076657 AAY82472 U43628 AAB02194 U82483 AAC13661 NM_130760 NP_570116 NM_130762 NP_570118
Function	Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L- selectin binding.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed on high endothelial venules (HEV) and lamina propia venules found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis, heart, placenta, lung, liver, skeletal muscle, kidney or peripheral blood leukocytes. {ECO:0000269|PubMed:8609404, ECO:0000269|PubMed:8989586}.
Top Pathways	Cell adhesion molecules (CAMs), Intestinal immune network for IgA production

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse MAdCAM-1 ELISA Kit (Sandwich ELISA) - LS-F2983 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 10 pg/ml Range 125-8000 pg/ml

Human MAdCAM-1 ELISA Kit (Sandwich ELISA) - LS-F4784 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 37 pg/ml Range 125-8000 pg/ml

Mouse MAdCAM-1 ELISA Kit (Custom ELISA) - LS-F392 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity To be determined Range 125-8000 pg/ml

Mouse MAdCAM-1 ELISA Kit (Sandwich ELISA) - LS-F8676 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.059 ng/ml Range 125-8000 pg/ml

Mouse MAdCAM-1 DuoSet ELISA - DY2768 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 125.00 - 8,000 pg/mL

Human MAdCAM-1 ELISA Kit - abx054719 from Abbexa Category ELISA Kit

Human MAdCAM1 ELISA Kit - abx152255 from Abbexa Category ELISA Kit Sensitivity 38 pg/ml Range 78.125 pg/ml - 5000 pg/ml

Mucosal Addressin Cell Adhesion Molecule 1, MAdCAM1, Human, ELISA Kit - E-EL-H1770 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mucosal Addressin Cell Adhesion Molecule 1 (MAdCAM1), Human, ELISA Kit - SEB521Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.125ng/mL Range 0.312-20ng/mL

Mucosal addressin cell adhesion molecule 1, MADCAM1, Human, ELISA Kit - E1521h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

Mucosal addressin cell adhesion molecule-1, MAdCAM-1, Human, ELISA Kit - CSB-E09940h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Mucosal vascular addressin cell adhesion molecule 1, Human, ELISA Kit - E01M0039 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 2.5-50ng/ml

Mucosal Addressin Cell Adhesion Molecule 1, MAdCAM1, Rabbit, ELISA Kit - E-EL-RB0821 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mucosal Addressin Cell Adhesion Molecule 1, MAdCAM1, Chicken, ELISA Kit - E-EL-Ch2242 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Mucosal Addressin Cell Adhesion Molecule 1, MAdCAM1, Porcine, ELISA Kit - E-EL-P1878 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Mucosal Addressin Cell Adhesion Molecule 1, MAdCAM1, Monkey, ELISA Kit - E-EL-MK0242 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human MAdCAM-1 ELISA Kit - HM0046 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine MADCAM-1 ELISA Kit - AM0046 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Mucosal vascular addressin cell adhesion molecule 1, ELISA Kit - MBS738126 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mucosal Vascular Addressin Cell Adhesion Molecule 1, ELISA Kit - MBS087385 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mucosal Vascular Addressin Cell Adhesion Molecule 1, ELISA Kit - MBS005473 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mucosal Vascular Addressin Cell Adhesion Molecule 1, ELISA Kit - MBS034923 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mucosal Vascular Addressin Cell Adhesion Molecule 1, ELISA Kit - MBS066415 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mucosal vascular addressin cell adhesion molecule 1, ELISA Kit - MBS725872 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,850.00, $5,340.00 Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive)

Mucosal Vascular Addressin Cell Adhesion Molecule 1, ELISA Kit - MBS104566 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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