Gene Symbol | Mbl1 |
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Entrez Gene | 17194 |
Alt Symbol | MBL-A, MBP-A, S-MBP |
Species | Mouse |
Gene Type | protein-coding |
Description | mannose-binding lectin (protein A) 1 |
Other Description | mannan-binding protein|mannose binding lectin (A)|mannose binding lectin, serum (A)|mannose-binding protein A|ra-reactive factor polysaccharide-binding component p28B|raRF p28B |
Swissprots | Q0P6H1 P39039 |
Accessions | AAA82009 EDL24920 P39039 AK034788 BC012245 AAH12245 BC021762 AAH21762 D11441 BAA02006 S42292 AAB19342 XM_006518669 XP_006518732 NM_010775 NP_034905 |
Function | Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. |
Top Pathways | Complement and coagulation cascades, Phagosome, Staphylococcus aureus infection |
MBL-A (A-13) - sc-103616 from Santa Cruz Biotechnology
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MBL-A (C-13) - sc-103617 from Santa Cruz Biotechnology
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MBL-A (M-54) - sc-292358 from Santa Cruz Biotechnology
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Anti-Mannan Binding Lectin A antibody [2B4] - ab36670 from Abcam
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Anti-Mbl1 Antibody - LS-C37282 from LifeSpan Bioscience
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Anti-Mbl1 Antibody (clone 2B4) - LS-C139868 from LifeSpan Bioscience
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Anti-Mbl1 Antibody (clone 13A138) - LS-C183028 from LifeSpan Bioscience
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Anti-Mbl1 Antibody (clone 8G6) - LS-C139867 from LifeSpan Bioscience
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MBL1 Antibody (8G6) - NBP1-60127 from Novus Biologicals
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MBL1 Antibody [Unconjugated] - AF2077 from Novus Biologicals
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MBL-A antibody [2B4] - GTX54386 from GeneTex
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MBL-A antibody [8G6] - GTX54385 from GeneTex
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Mouse MBL-1 Antibody - AF2077 from R&D Systems
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Mouse MBL-1 Affinity Purified Polyclonal Ab, Goat IgG - AF2077-SP from R&D Systems
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Anti -MBL-A (Mannose-binding Protein A, Mannan-binding Protein, Ra-reactive FactorPolysaccharide-binding Component p28B, RaRF p28B, Mbl1) - M2250-22 from USBiological Life Science
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Anti -MBL-A (Mannose-binding Protein A, Mannan-binding Protein, Ra-reactive FactorPolysaccharide-binding Component p28B, RaRF p28B, Mbl1) - M2250-22A from USBiological Life Science
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MBL-A antibody - AM26334PU-N from Acris Antibodies
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MBL-A antibody - AM26335PU-N from Acris Antibodies
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MBL-A, Monoclonal Antibody - MBS584013 from MyBioSource
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MBL-A, Monoclonal Antibody - MBS584309 from MyBioSource
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MBL-A, Monoclonal Antibody - MBS6006438 from MyBioSource
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MBL-A, Monoclonal Antibody - MBS646118 from MyBioSource
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Anti-MBL1 monoclonal antibody, clone 3C5 - CABT-35175RM from Creative Diagnostics
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