Grm5

Gene Symbol Grm5
Entrez Gene 24418
Alt Symbol mGluR5, mGlur5
Species Rat
Gene Type protein-coding
Description glutamate receptor, metabotropic 5
Other Description metabotropic glutamate receptor (mGluR5)|metabotropic glutamate receptor 5|metabotropic glutamate receptor 5b
Swissprots P31424
Accessions EDM18590 EDM18591 P31424 D10891 BAA01711 EU559292 ACB45671 XM_006229659 XP_006229721 NM_017012 NP_058708
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. {ECO:0000269|PubMed:1320017, ECO:0000269|PubMed:21795692}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:1320017}; Multi-pass membrane protein {ECO:0000269|PubMed:1320017}.
Tissue Specificity Widely distributed in neuronal cells of the central nervous system. {ECO:0000269|PubMed:1320017, ECO:0000269|PubMed:21795692}.
Top Pathways Gap junction, Long-term potentiation, Huntington's disease, Calcium signaling pathway, Glutamatergic synapse

Anti-GRM1a / GRM5 Antibody (C-Terminus) - LS-C66638 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

metabotropic Glutamate Receptor 5/1 Antibody - NB300-126 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: metabotropic Glutamate Receptor 5/1 Antibody [NB300-126] - 10 ug of HEK 293 cells expression. As shown in the autoradiograph, the mGluR5/1a antibody recognizes both mGluR5 (Lane A) and mGluR1a (Lane B) labeling the ~125k monomer and the ~250k dimers for both mGluRs.

metabotropic Glutamate Receptor 5/1 Antibody (S75-3) - NBP2-22424 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-3
Western Blot: metabotropic Glutamate Receptor 5/1 Antibody (S75-3) [NBP2-22424] - analysis of Rat Brain Membrane showing detection of 130 kDa mGluR5 protein using Mouse Anti-mGluR5 Monoclonal Antibody, Clone S75-33. Lane 1: MW Ladder. Lane 2: Rat Brain Membrane (10 ug).. Load: 10 ug. Block: 5% milk. Primary Antibody: Mouse Anti-mGluR5 Monoclonal Antibody at 1:1000 for 1 hour at RT. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: TMB solution for 10 min at RT. Predicted/Observed Size: 130 kDa.

Monoclonal Anti-Mglur1/5 - Streptavidin antibody produced in mouse - SAB5200725 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33

Monoclonal Anti-Mglur1/5 - Fitc antibody produced in mouse - SAB5200504 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Atto 680 antibody produced in mouse - SAB5200715 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of ATTO 680 dye

Monoclonal Anti-Mglur1/5 - Atto 390 antibody produced in mouse - SAB5200493 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Percp antibody produced in mouse - SAB5200507 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Atto 633 antibody produced in mouse - SAB5200713 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of ATTO 633 dye

Monoclonal Anti-Mglur1/5 - Rpe antibody produced in mouse - SAB5200508 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Atto 565 antibody produced in mouse - SAB5200711 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of ATTO 565 dye

Monoclonal Anti-Mglur1/5 - Atto 700 antibody produced in mouse - SAB5200716 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of ATTO 700 dye

Monoclonal Anti-Mglur1/5 - Biotin antibody produced in mouse - SAB5200719 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33

Monoclonal Anti-Mglur1/5 - Fitc antibody produced in mouse - SAB5200720 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of FITC

Monoclonal Anti-Mglur1/5 - Atto 488 antibody produced in mouse - SAB5200494 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Pe/Atto 594 antibody produced in mouse - SAB5200722 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of PE+ATTO 594 dye

Monoclonal Anti-Mglur1/5 antibody produced in mouse - SAB5200708 from Sigma-Aldrich

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33

Monoclonal Anti-Mglur1/5 - Atto 594 antibody produced in mouse - SAB5200496 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Atto 680 antibody produced in mouse - SAB5200499 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Streptavidin antibody produced in mouse - SAB5200509 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33

Monoclonal Anti-Mglur1/5 - Rpe antibody produced in mouse - SAB5200724 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of R-PE

Monoclonal Anti-Mglur1/5 - Atto 700 antibody produced in mouse - SAB5200500 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Atto 655 antibody produced in mouse - SAB5200714 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
Representative absorption and emission spectra chart of ATTO 655 dye

Monoclonal Anti-Mglur1/5 antibody produced in mouse - SAB5200492 from Sigma-Aldrich

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.

Monoclonal Anti-Mglur1/5 - Pe/Atto 594 antibody produced in mouse - SAB5200506 from Sigma-Aldrich

Prices $395.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone S75-33
<B>Immunoblotting</B><BR/>Monoclonal Anti-mGluR1/5: Western Blot analysis of Rat brain membrane lysate using mGluR5 Glutamate Receptor antibody at a dilution of 1:1,000.
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